Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134202 | 0.77 | KDM4E (0.45) | ALDH1A1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL10816262 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL10731969 | 0.75 | CTSD (0.52) | ALDH1A1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL4044963 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHR | |
| SCHEMBL27747937 | 0.71 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL220310 | 0.69 | KDM4E (0.77) | ALDH1A1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL2744516 | 0.69 | — | — | |
| SCHEMBL11850983 | 0.68 | MEN1 (0.47) | ALDH1A1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL14967439 | 0.67 | PHF8 (0.52) | ALDH1A1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL31364147 | 0.67 | KDM4E (0.52) | ALDH1A1KDM4EKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1543096-B1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | CHEMTURA CORP (US) | 2008-04-30 | — | — | EP | claimed |
| CN-1272415-C | Alkyl succinhydrazide additive for lubricant | UNIROYAL CHEM CO INC (US) | 2006-08-30 | — | — | CN | claimed |
| EP-1543096-A1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | Uniroyal Chemical Company, Inc. (US) | 2005-06-22 | — | — | EP | claimed |
| CN-1606611-A | Alkyl succinite hydrazide additive for lubricant | UNIROYAL CHEM CO INC (US) | 2005-04-13 | — | — | CN | claimed |
| WO-2004029183-A1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2004-04-08 | — | — | WO | claimed |
| US-6706671-B2 | A LUBRICANT, AND 4-ALKYL-1,2-DIHYDROPYRIDAZINE-3,6-DIONES, WHICH IS ASHLESS AND NONPHOSPHORUS CONTAINING ANTIWEAR, ANTIFATIGUE AND EXTREEM PRESSURE ADDITIVE | UNIROYAL CHEMICAL COMPANY, INC. | 2004-03-16 | — | — | US | claimed |
| US-20030104953-A1 | A lubricant, and 4-alkyl-1,2-dihydropyridazine-3,6-diones, which is ashless and nonphosphorus containing antiwear, antifatigue and extreem pressure additive | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-05 | — | — | US | claimed |
| EP-1543096-B1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | CHEMTURA CORP (US) | 2008-04-30 | — | — | EP | disclosed |
| EP-1543096-B1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | CHEMTURA CORP (US) | 2008-04-30 | — | — | EP | disclosed |
| CN-1272415-C | Alkyl succinhydrazide additive for lubricant | UNIROYAL CHEM CO INC (US) | 2006-08-30 | — | — | CN | disclosed |
| EP-1543096-A1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | Uniroyal Chemical Company, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1543096-A1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | Uniroyal Chemical Company, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| CN-1606611-A | Alkyl succinite hydrazide additive for lubricant | UNIROYAL CHEM CO INC (US) | 2005-04-13 | — | — | CN | disclosed |
| WO-2004029183-A1 | ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| US-6706671-B2 | A LUBRICANT, AND 4-ALKYL-1,2-DIHYDROPYRIDAZINE-3,6-DIONES, WHICH IS ASHLESS AND NONPHOSPHORUS CONTAINING ANTIWEAR, ANTIFATIGUE AND EXTREEM PRESSURE ADDITIVE | UNIROYAL CHEMICAL COMPANY, INC. | 2004-03-16 | — | — | US | disclosed |
| US-6706671-B2 | A LUBRICANT, AND 4-ALKYL-1,2-DIHYDROPYRIDAZINE-3,6-DIONES, WHICH IS ASHLESS AND NONPHOSPHORUS CONTAINING ANTIWEAR, ANTIFATIGUE AND EXTREEM PRESSURE ADDITIVE | UNIROYAL CHEMICAL COMPANY, INC. | 2004-03-16 | — | — | US | disclosed |
| US-6706671-B2 | A LUBRICANT, AND 4-ALKYL-1,2-DIHYDROPYRIDAZINE-3,6-DIONES, WHICH IS ASHLESS AND NONPHOSPHORUS CONTAINING ANTIWEAR, ANTIFATIGUE AND EXTREEM PRESSURE ADDITIVE | UNIROYAL CHEMICAL COMPANY, INC. | 2004-03-16 | — | — | US | disclosed |
| US-20030104953-A1 | A lubricant, and 4-alkyl-1,2-dihydropyridazine-3,6-diones, which is ashless and nonphosphorus containing antiwear, antifatigue and extreem pressure additive | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-05 | — | — | US | disclosed |
| US-20030104953-A1 | A lubricant, and 4-alkyl-1,2-dihydropyridazine-3,6-diones, which is ashless and nonphosphorus containing antiwear, antifatigue and extreem pressure additive | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-05 | — | — | US | disclosed |
| US-20030104953-A1 | A lubricant, and 4-alkyl-1,2-dihydropyridazine-3,6-diones, which is ashless and nonphosphorus containing antiwear, antifatigue and extreem pressure additive | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-05 | — | — | US | disclosed |