Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615678 | 0.77 | ALDH1A1 (0.46) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| SCHEMBL220310 | 0.72 | KDM4E (0.77) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| SCHEMBL31364147 | 0.70 | KDM4E (0.52) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| SCHEMBL14967439 | 0.70 | PHF8 (0.52) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| Hydrazine SCHEMBL28064827 | 0.69 | KDM4E (0.72) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| SCHEMBL10731969 | 0.69 | CTSD (0.52) | KDM4EKDM5CPHF8KDM2AALDH1A1 | |
| SCHEMBL27943029 | 0.69 | — | — | |
| SCHEMBL4603687 | 0.68 | FAAH (0.45) | KDM4EMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2744516 | 0.67 | — | — | |
| SCHEMBL28814977 | 0.67 | ALDH1A1 (0.51) | KDM4EKDM5CPHF8KDM2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927196-B1 | POLYMERS CONTAINING POLYSACCHARIDES SUCH AS ALGINATES OR MODIFIED ALGINATES | UNIV MICHIGAN (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1806367-A2 | Polymers containing polysaccharides such as alginates or modified alginates | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-07-11 | — | — | EP | disclosed |
| US-6642363-B1 | Bonded to a peptide which promotes cell adhesion and growth; use in drug delivery, cell transplantation and tissue engineering | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2003-11-04 | — | — | US | disclosed |
| EP-1117444-A2 | HYDROGELS AND WATER SOLUBLE POLYMERIC CARRIERS FOR DRUG DELIVERY | THE UNIVERSITY OF MICHIGAN (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-0927196-A4 | POLYMERS CONTAINING POLYSACCHARIDES SUCH AS ALGINATES OR MODIFIED ALGINATES | UNIV MICHIGAN (US) | 2000-12-13 | — | — | EP | disclosed |
| WO-2000021572-A2 | HYDROGELS AND WATER SOLUBLE POLYMERIC CARRIERS FOR DRUG DELIVERY | THE UNIVERSITY OF MICHIGAN (US) | 2000-04-20 | — | — | WO | disclosed |
| EP-0927196-A1 | POLYMERS CONTAINING POLYSACCHARIDES SUCH AS ALGINATES OR MODIFIED ALGINATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998012228-A1 | POLYMERS CONTAINING POLYSACCHARIDES SUCH AS ALGINATES OR MODIFIED ALGINATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-03-26 | — | — | WO | disclosed |