Malonic Acid

Malonic Acid

SCHEMBL4616181

CCCC[Sn+2]CCCC.O=C([O-])CC(=O)[O-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.48
CA1 P00915 1/20 0.46
CES1 P23141 6/20 0.40
CES2 O00748 5/20 0.40
FFAR3 O14843 2/20 0.40
HDAC3 O15379 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
FABP3 P05413 2/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL825458 0.89 CA1 (0.41) CA4CA1CES1CES2FFAR3
Propionic Acid SCHEMBL8359110 0.88 CA1 (0.48) CA1CES1CES2FFAR3HDAC3
Bicarbonate SCHEMBL27704869 0.87 CA1 (0.46) CA1CES1CES2FFAR3HDAC3
Acetoacetic Acid SCHEMBL30244954 0.87 CA1 (0.40) CA4CA1CES1CES2FFAR3
Succinic Acid SCHEMBL3977804 0.86 CA1 (0.58) CA1CES1CES2FFAR3HDAC3
Glycolic Acid SCHEMBL630796 0.86 CA1 (0.46) CA1CES1CES2FFAR3HDAC3
SCHEMBL1229427 0.86 CA1 (0.43) CA1CES1CES2FFAR3HDAC3
Acetic Acid SCHEMBL37323 0.85 CES1 (0.44) CA1CES1CES2FFAR3HDAC3
Oxalic Acid SCHEMBL4020981 0.85 CA1 (0.44) CA1CES1CES2FFAR3HDAC3
SCHEMBL30647271 0.84 CA1 (0.42) CA1CES1CES2FFAR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114561036-B Preparation method of silicon-based phosphoric acid flame-retardant composite foam material 南京焱禾新材料科技有限公司 2023-12-05 CN claimed
CN-114561036-A Preparation method of silicon-based phosphoric acid flame-retardant composite foam material 陈泊萍 2022-05-31 CN claimed
CN-111647128-B Preparation method of formaldehyde-free textile color fixing agent 义乌市渊泰新材料有限公司 2021-11-12 CN claimed
CN-111647128-A Preparation method of formaldehyde-free textile color fixing agent 义乌市渊泰新材料有限公司 2020-09-11 CN claimed
CN-118652498-A Basalt fiber reinforced polypropylene composite material and preparation method and application thereof 北京好运达智创科技有限公司 2024-09-17 CN disclosed
CN-114561036-B Preparation method of silicon-based phosphoric acid flame-retardant composite foam material 南京焱禾新材料科技有限公司 2023-12-05 CN disclosed
CN-112204076-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2023-10-24 CN disclosed
CN-114561036-A Preparation method of silicon-based phosphoric acid flame-retardant composite foam material 陈泊萍 2022-05-31 CN disclosed
CN-111647128-B Preparation method of formaldehyde-free textile color fixing agent 义乌市渊泰新材料有限公司 2021-11-12 CN disclosed
CN-112513187-A Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2021-03-16 CN disclosed
CN-112204076-A Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2021-01-08 CN disclosed
CN-111647128-A Preparation method of formaldehyde-free textile color fixing agent 义乌市渊泰新材料有限公司 2020-09-11 CN disclosed
US-7314947-B2 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES (US) 2008-01-01 US disclosed
US-7279592-B2 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES (US) 2007-10-09 US disclosed
EP-1740529-A2 PROCESS FOR MAKING DIALKYL CARBONATES Catalytic Distillation Technologies (US) 2007-01-10 EP disclosed
US-7074951-B2 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES 2006-07-11 US disclosed
US-20060142607-A1 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES 2006-06-29 US disclosed
US-20060142606-A1 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES 2006-06-29 US disclosed
WO-2005102986-A2 PROCESS FOR MAKING DIALKYL CARBONATES CATALYTIC DISTILLATION TECHNOLOGIES (US) 2005-11-03 WO disclosed
US-20050203307-A1 Process for making dialkyl carbonates CATALYTIC DISTILLATION TECHNOLOGIES 2005-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142606-A1 Process for making dialkyl carbonates ADH1C, CPS1, C1S CA4 217/4885CA1 284/4885CES1 437/4885
US-20060142607-A1 Process for making dialkyl carbonates ADH1C, CPS1, C1S CA4 217/4885CA1 284/4885CES1 437/4885
US-20050203307-A1 Process for making dialkyl carbonates ADH1C, CPS1, C1S CA4 217/4885CA1 284/4885CES1 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.