Acetoacetic Acid

Acetoacetic Acid

SCHEMBL825458

CC(=O)CC(=O)[O-].CC(=O)CC(=O)[O-].CCCC[Sn+2]CCCC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CES1 P23141 6/20 0.37
CA4 P22748 2/20 0.36
CES2 O00748 5/20 0.36
FFAR3 O14843 2/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
FABP3 P05413 2/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL30244954 0.98 CA1 (0.40) CA1CES1CA4CES2FFAR3
Acetoacetic Acid SCHEMBL29373241 0.92 CES2 (0.40) CA1CES1CES2FABP3
Malonic Acid SCHEMBL4616181 0.89 CA4 (0.48) CA1CES1CA4CES2FFAR3
SCHEMBL825287 0.86 CES1 (0.35) CA1CES1CES2FABP3
Acetic Acid SCHEMBL37323 0.84 CES1 (0.44) CA1CES1CES2FFAR3HDAC3
Acetic Acid SCHEMBL7541149 0.82 CES1 (0.42) CA1CES1CES2FFAR3HDAC3
Acetic Acid SCHEMBL31411090 0.82 CA1 (0.48) CA1CES1CES2FFAR3HDAC3
Acetic Acid SCHEMBL28521370 0.82 CES1 (0.42) CA1CES1CES2FFAR3HDAC3
Acetic Acid SCHEMBL21836054 0.82 CA1 (0.48) CA1CES1CES2FFAR3HDAC3
Acetic Acid SCHEMBL2139863 0.82 CA1 (0.48) CA1CES1CES2FFAR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421419-B2 Preparation method for ultraviolet-responsive coumarin controlled-release and self-repairing anti-fouling paint Quzhou Research Institute of Zhejiang University (CN) 2025-09-23 US claimed
US-20230212419-A1 PREPARATION METHOD FOR ULTRAVIOLET-RESPONSIVE COUMARIN CONTROLLED-RELEASE AND SELF-REPAIRING ANTI-FOULING PAINT Quzhou Research Institute of Zhejiang University (CN) 2023-07-06 US claimed
CN-113897171-B Preparation method of high-displacement dealcoholized flame-retardant fireproof sealant 成都硅宝科技股份有限公司 2023-02-03 CN claimed
WO-2022160853-A1 PREPARATION METHOD FOR ANTI-FOULING COATING CAPABLE OF CONTROLLED RELEASE OF ULTRAVIOLET-RESPONSIVE COUMARIN AND SELF-REPAIR 浙江大学衢州研究院 2022-08-04 WO claimed
CN-113150594-B Preparation method of ultraviolet-response coumarin controlled-release and self-repair antifouling paint 浙江大学衢州研究院 2022-06-21 CN claimed
CN-113150594-A Preparation method of ultraviolet-response coumarin controlled-release and self-repair antifouling paint 浙江大学衢州研究院 2021-07-23 CN claimed
US-10385245-B2 One-component moisture-curable urethane composition and method for producing same THE YOKOHAMA RUBBER CO., LTD. (JP) 2019-08-20 US claimed
US-20180346773-A1 ADHESIVE FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-06 US claimed
US-20170158927-A1 One-Component Moisture-Curable Urethane Composition and Method for Producing Same THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-06-08 US claimed
WO-2017062252-A1 ADHESIVE FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2017-04-13 WO claimed
US-20090098384-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ANTIFOULING COMPOSITE COATING FILM CHUGOKU MARINE PAINTS, LTD. (JP) 2009-04-16 US claimed
EP-1990366-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ANTIFOULING COMPOSITE COATING FILM CHUGOKU MARINE PAINTS, LTD. (JP) 2008-11-12 EP claimed
US-6855779-B1 High solid epoxy, melamine and isocyanate compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-02-15 US claimed
JP-2003525966-A 2003-09-02 JP claimed
EP-1233992-A1 HIGH SOLID EPOXY, MELAMINE AND ISOCYANATE COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-08-28 EP claimed
WO-2000055231-A1 HIGH SOLID EPOXY, MELAMINE AND ISOCYANATE COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-09-21 WO claimed
EP-4450562-B1 ALKOXYSILYL GROUP-CONTAINING PERFLUOROPOLYETHER COMPOUND, AND COMPOSITION CONTAINING SAME SHINETSU CHEMICAL CO (JP) 2026-04-15 EP disclosed
US-20260035925-A1 METHOD FOR SEALING ROOFING MEMBRANES SIKA TECHNOLOGY AG (CH) 2026-02-05 US disclosed
WO-1998011166-A1 POLYMER COMPOSITION COMPRISING A MODIFYING AGENT LANDEC CORPORATION (US) 1998-03-19 WO disclosed
WO-1997019120-A1 WATER-DISPERSIBLE UNSATURATED POLYURETHANE AKZO NOBEL N.V. (NL) 1997-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035925-A1 METHOD FOR SEALING ROOFING MEMBRANES GJA1, LNPK, VMP1 CA1 337/4885CES1 1806/4885CA4 3028/4885
US-20090098384-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ANTIFOULING COMPOSITE COATING FILM FUCA1, CELA1, IDUA CA1 480/4885CES1 77/4885CA4 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.