Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4616679

C=C(C)C(=O)OC(C)C[N+](CC)(CC)CC.[Cl-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.40
CHRM1 known ✓ P11229 2/20 0.40
CHRM3 known ✓ P20309 1/20 0.35
MAPT P10636 2/20 0.43
GALR3 O60755 1/20 0.43
BLM P54132 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 5/20 0.40
CHRM4 P08173 2/20 0.40
TBXA2R P21731 1/20 0.40
LMNA P02545 2/20 0.38
THRB P10828 1/20 0.38
CHRM5 P08912 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28330589 0.98 TSHR (0.41) MAPTGALR3BLMSMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL21880081 0.84 MAPT (0.46) MAPTGALR3BLMSMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL31358625 0.82 TSHR (0.36) MAPTGALR3BLMSMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL717993 0.81 MAPT (0.66) MAPTGALR3BLMSMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL2798754 0.81 THRB (0.37) MAPTGALR3BLMSMN1; SMN2TSHR
SCHEMBL202123 0.79 TSHR (0.64) MAPTGALR3BLMSMN1; SMN2TSHR
SCHEMBL15253677 0.79 TSHR (0.46) SMN1; SMN2TSHRLMNAALDH1A1
SCHEMBL16352961 0.79 TSHR (0.63) MAPTGALR3BLMSMN1; SMN2TSHR
SCHEMBL28039239 0.79 TSHR (0.47) MAPTGALR3BLMSMN1; SMN2TSHR
SCHEMBL33467 0.77 TSHR (0.48) MAPTGALR3BLMSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1543983-B1 Ink-jet recording medium and process for producing the same FUJIFILM CORP (JP) 2008-02-20 EP disclosed
US-20050158489-A1 Ink-jet recording medium and process for producing the same FUJI PHOTO FILM CO., LTD. 2005-07-21 US disclosed
EP-1543983-A1 Ink-jet recording medium and process for producing the same Fuji Photo Film Co., Ltd. (JP) 2005-06-22 EP disclosed