Hydrochloric Acid

Hydrochloric Acid

SCHEMBL717993

C=C(C)C(=O)OC(C)C[N+](C)(C)C.[Cl-]

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.62
CHRM1 known ✓ P11229 2/20 0.62
CHRM3 known ✓ P20309 1/20 0.55
MAPT P10636 3/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
GALR3 O60755 1/20 0.66
BLM P54132 1/20 0.66
TSHR P16473 5/20 0.62
CHRM4 P08173 2/20 0.62
TBXA2R P21731 1/20 0.62
LMNA P02545 3/20 0.58
CHRM5 P08912 1/20 0.55
CYP2C9 P11712 1/20 0.55
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
HRH1 P35367 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202123 0.98 TSHR (0.64) MAPTSMN1; SMN2GALR3BLMTSHR
Acrylamide SCHEMBL28572441 0.89 LMNA (0.56) MAPTSMN1; SMN2GALR3BLMTSHR
Hydrochloric Acid SCHEMBL21880081 0.84 MAPT (0.46) MAPTSMN1; SMN2GALR3BLMTSHR
Hydrochloric Acid SCHEMBL27784122 0.82 MAPT (0.47) MAPTSMN1; SMN2GALR3BLMTSHR
SCHEMBL28243765 0.81 TSHR (0.44) MAPTSMN1; SMN2GALR3BLMTSHR
Hydrochloric Acid SCHEMBL4616679 0.81 MAPT (0.43) MAPTSMN1; SMN2GALR3BLMTSHR
Methacholine SCHEMBL69104 0.79 MAPT (1.00) MAPTSMN1; SMN2GALR3BLMTSHR
Hydrochloric Acid SCHEMBL2879910 0.79 MAPT (0.44) MAPTSMN1; SMN2GALR3BLMTSHR
SCHEMBL28330589 0.79 TSHR (0.41) MAPTSMN1; SMN2GALR3BLMTSHR
Hydrochloric Acid SCHEMBL8993341 0.78 LMNA (0.46) MAPTSMN1; SMN2GALR3BLMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101432231-A A filter for water potabilization and a process for realisation of the filter UFI FILTERS SPA (IT) 2009-05-13 CN claimed
EP-1159318-B1 OLIGOMERIZATION AND (CO)POLYMERIZATION OF SUBSTITUTED AND UNSUBSTITUTED ALPHA-METHYLENE-GAMMA-BUTYROLACTONES AND PRODUCTS THEREOF DU PONT (US) 2004-01-21 EP claimed
US-6388036-B1 USING FREE RADICAL CATALYST AND CHAIN TRANSFER AGENT; MOLECULAR WEIGHT CONTROL E. I. DU PONT DE NEMOURS AND COMPANY 2002-05-14 US claimed
EP-1159318-A2 OLIGOMERIZATION AND (CO)POLYMERIZATION OF SUBSTITUTED AND UNSUBSTITUTED ALPHA-METHYLENE-GAMMA-BUTYROLACTONES AND PRODUCTS THEREOF E.I. DUPONT DE NEMOURS AND COMPANY (US) 2001-12-05 EP claimed
WO-2000035960-A2 OLIGOMERIZATION, POLYMERIZATION AND COPOLYMERIZATION OF SUBSTITUTED AND UNSUBSTITUTED α-METHYLENE-η-BUTYROLACTONES AND PRODUCTS THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-22 WO claimed
EP-1003793-A1 FUNCTIONALIZED DIENE OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-31 EP claimed
WO-1999009077-A1 FUNCTIONALIZED DIENE OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-25 WO claimed
US-5847060-A Functionalized diene oligomers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-08 US claimed
CN-113242891-B Polishing slurry composition 凯斯科技股份有限公司 2023-02-28 CN disclosed
CN-113242891-A Polishing slurry composition 凯斯科技股份有限公司 2021-08-10 CN disclosed
CN-112930377-A Polishing slurry composition and method for preparing the same 凯斯科技股份有限公司 2021-06-08 CN disclosed
EP-2118227-B1 POLISHING COMPOSITION FOR TUNGSTEN-CONTAINING SUBSTRATE CABOT MICROELECTRONICS CORP (US) 2017-09-13 EP disclosed
US-9579608-B2 Composite membranes and methods of preparation thereof GLOBALFOUNDRIES INC. (KY) 2017-02-28 US disclosed
US-9352286-B2 Composite filtration membranes and methods of preparation thereof GLOBALFOUNDRIES INC. (KY) 2016-05-31 US disclosed
WO-1999009077-A1 FUNCTIONALIZED DIENE OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-25 WO disclosed
EP-0888388-A1 FREE RADICAL POLYMER CHAIN INITIATION WITH UNREACTIVE UNSATURATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-07 EP disclosed
US-5847060-A Functionalized diene oligomers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-08 US disclosed
EP-0830952-A2 Ink jet recording sheet KONICA CORPORATION (JP) 1998-03-25 EP disclosed
WO-1997034934-A1 FREE RADICAL POLYMER CHAIN INITIATION WITH UNREACTIVE UNSATURATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-25 WO disclosed
EP-0480162-A1 Dyeing method and dyed product MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1992-04-15 EP disclosed