Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.95 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29438523 | 1.00 | HDAC8 (0.95) | HDAC8ACHETSHRHRH1PDE4D | |
| SCHEMBL589251 | 0.98 | — | — | |
| SCHEMBL29961324 | 0.98 | — | — | |
| Bromide SCHEMBL367171 | 0.95 | HDAC8 (0.95) | HDAC8ACHETSHRHRH1PDE4D | |
| Iodide SCHEMBL997529 | 0.95 | HDAC8 (0.95) | HDAC8ACHETSHRHRH1PDE4D | |
| Fluoride Ion SCHEMBL7937290 | 0.95 | HDAC8 (0.95) | HDAC8ACHETSHRHRH1PDE4D | |
| Bromide SCHEMBL29392397 | 0.95 | HDAC8 (0.95) | HDAC8ACHETSHRHRH1PDE4D | |
| Water SCHEMBL9445012 | 0.95 | HDAC8 (0.95) | HDAC8ACHETSHRHRH1PDE4D | |
| SCHEMBL5162131 | 0.90 | HDAC8 (0.84) | HDAC8ACHETSHRHRH1PDE4D | |
| SCHEMBL19971548 | 0.90 | HDAC8 (0.84) | HDAC8ACHETSHRHRH1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045544-B1 | SUPER ADVANCED CONTROLLED RADICAL POLYMERIZATION | BASF COATINGS GMBH (DE) | 2026-03-18 | — | — | EP | claimed |
| US-12534561-B2 | Controlled radical polymerization | BASF COATINGS GMBH (DE) | 2026-01-27 | — | — | US | claimed |
| EP-4001367-B1 | AQUEOUS INKJET INK COMPOSITIONS MADE FROM HIGH VISCOSITY LATEXES | XEROX CORP (US) | 2026-01-07 | — | — | EP | claimed |
| US-12257553-B2 | Separation membrane and methods of preparation thereof | ASPEN PRODUCTS GROUP, INC. (US) | 2025-03-25 | — | — | US | claimed |
| US-20240294689-A1 | SUPER ADVANCED CONTROLLED RADICAL POLYMERIZATION | BASF COATINGS GMBH (DE) | 2024-09-05 | — | — | US | claimed |
| EP-4001369-B1 | AQUEOUS INKJET INK COMPOSITIONS MADE FROM MONODISPERSE LATEXES | XEROX CORP (US) | 2023-06-21 | — | — | EP | claimed |
| EP-4045544-A1 | SUPER ADVANCED CONTROLLED RADICAL POLYMERIZATION | BASF Coatings GmbH (DE) | 2022-08-24 | — | — | EP | claimed |
| CN-114514256-A | Ultra high end controlled free radical polymerization | 巴斯夫涂料有限公司 | 2022-05-17 | — | — | CN | claimed |
| US-20220032240-A1 | Separation Membrane and Methods of Preparation Thereof | ASPEN PRODUCTS GROUP, INC. (US) | 2022-02-03 | — | — | US | claimed |
| WO-2022026968-A1 | SEPARATION MEMBRANE AND METHODS OF PREPARATION THEREOF | ASPEN PRODUCTS GROUP, INC. (US) | 2022-02-03 | — | — | WO | claimed |
| US-5561025-A | Toner aggregation processes | XEROX CORPORATION (US) | 1996-10-01 | — | — | US | claimed |
| EP-0263647-B1 | PVA gel | SHINETSU CHEMICAL CO (JP) | 1994-01-05 | — | — | EP | claimed |
| US-5093130-A | Free-flowing, plants, seeds | PLANT GENETICS (US) | 1992-03-03 | — | — | US | claimed |
| EP-0263647-A2 | PVA gel | Shin-Etsu Chemical Co., Ltd. (JP) | 1988-04-13 | — | — | EP | claimed |
| US-4728556-A | POLYMERIC ELECTROLYTE, INORGANIC SALT OR SURFACTANT IN DOTS ON SURFACE | RICOH COMPANY, LTD. (JP) | 1988-03-01 | — | — | US | claimed |
| US-4715143-A | Artificial seed coat for botanic seed analogs | PLANT GENETICS, INC. (US) | 1987-12-29 | — | — | US | claimed |
| EP-0116151-B1 | PROCESS FOR THE REGENERATION OR RECYCLING OF AQUEOUS DEGREASING AND CLEANING SOLUTIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-05-20 | — | — | EP | claimed |
| US-4603176-A | Temporary wet strength resins | THE PROCTER & GAMBLE COMPANY (US) | 1986-07-29 | — | — | US | claimed |
| US-4396667-A | CONDUCTIVE CATIONIC POLYELECTROLYTE | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-08-02 | — | — | US | claimed |
| US-3983564-A | Image recording member | CANON KABUSHIKI KAISHA (JA) | 1976-09-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534561-B2 | Controlled radical polymerization | TST, G6PD, PROC | ACHE 267/4885HDAC8 4393/4885TSHR 2496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.