Bromide

Bromide

SCHEMBL367171

C=Cc1cccc[n+]1C.[Br-]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 2/20 0.57
HDAC8 Q9BY41 5/20 0.95
TSHR P16473 1/20 0.53
HRH1 P35367 1/20 0.53
PDE4D Q08499 1/20 0.53
KDM4E B2RXH2 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
CTDSP1 Q9GZU7 1/20 0.52
RAB9A P51151 4/20 0.47
PABPC1 P11940 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
CHAT P28329 1/20 0.43
EIF4H Q15056 1/20 0.42
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL29392397 1.00 HDAC8 (0.95) HDAC8ACHETSHRHRH1PDE4D
SCHEMBL589251 0.98
SCHEMBL29961324 0.98
Water SCHEMBL9445012 0.95 HDAC8 (0.95) HDAC8ACHETSHRHRH1PDE4D
Hydrochloric Acid SCHEMBL29438523 0.95 HDAC8 (0.95) HDAC8ACHETSHRHRH1PDE4D
Iodide SCHEMBL997529 0.95 HDAC8 (0.95) HDAC8ACHETSHRHRH1PDE4D
Fluoride Ion SCHEMBL7937290 0.95 HDAC8 (0.95) HDAC8ACHETSHRHRH1PDE4D
Hydrochloric Acid SCHEMBL461720 0.95 HDAC8 (0.95) HDAC8ACHETSHRHRH1PDE4D
SCHEMBL5162131 0.90 HDAC8 (0.84) HDAC8ACHETSHRHRH1PDE4D
SCHEMBL19971548 0.90 HDAC8 (0.84) HDAC8ACHETSHRHRH1PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144617-A1 ORTHODONTIC CHEW, COMFORT TAPE, AND STICKER FOR THERAPEUTIC USE AND WOUND CARE ORTHONU LLC (US) 2026-05-28 US claimed
US-12600817-B2 Devices and methods for analyzing biological samples Cellanome, Inc. (US) 2026-04-14 US claimed
US-20260061062-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM UNIV NEBRASKA (US) 2026-03-05 US claimed
US-20250282912-A1 DEVICES AND METHODS FOR ANALYZING BIOLOGICAL SAMPLES Cellanome, Inc. 2025-09-11 US claimed
WO-2024163331-A1 POLYMER-METAL ORGANIC FRAMEWORK COMPOSITES AND METHODS OF CAPTURING CO2 UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2024-08-08 WO claimed
EP-3600220-B1 POLYPHENOLS/PEG BASED HYDROGEL SYSTEM FOR A DENTAL VARNISH DENTSPLY SIRONA INC (US) 2023-03-22 EP claimed
US-20220015943-A1 BALLISTIC DELIVERY AND RELATED PARTICLES, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2022-01-20 US claimed
US-20220008543-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-01-13 US claimed
CN-113226376-A Thermosensitive injectable gels based on macromolecular prodrugs as novel drug delivery platform 内布拉斯加大学董事会 2021-08-06 CN claimed
EP-3787624-A2 CAPSULE-IN-CAPSULE COMPOSITIONS OF DABIGATRAN ETEXILATE Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi (TR) 2021-03-10 EP claimed
US-20100193999-A1 ELECTROSPINNING OF PTFE WITH HIGH VISCOSITY MATERIALS ZEUS COMPANY LLC 2010-08-05 US claimed
WO-2008112086-A2 ELECTROPLATING PROCESS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-18 WO claimed
US-20080217182-A1 Forming metal layers into recesses on electroconductive surfaces; forming integrated circuit patterns; overcoating semiconductor wafer E. I. DUPONT DE NEMOURS AND COMPANY (US) 2008-09-11 US claimed
US-20080159959-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2008-07-03 US claimed
EP-1737428-A1 MACROMOLECULAR DELIVERY SYSTEMS FOR NON-INVASIVE IMAGING, EVALUATION AND TREATMENT OF ARTHRITIS AND OTHER INFLAMMATORY DISEASES University of Utah Research Foundation (US) 2007-01-03 EP claimed
US-20050287114-A1 Water-soluble polymeric bone-targeting drug delivery system UNIVERSITY OF UTAH RESEARCH FOUNDATION 2005-12-29 US claimed
WO-2005097073-A1 MACROMOLECULAR DELIVERY SYSTEMS FOR NON-INVASIVE IMAGING, EVALUATION AND TREATMENT OF ARTHRITIS AND OTHER INFLAMMATORY DISEASES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2005-10-20 WO claimed
US-20040200993-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2004-10-14 US claimed
WO-2004062588-A2 WATER-SOLUBLE POLYMERIC BONE-TARGETING DRUG DELIVERY SYSTEM UNIVERSITY OF UTAH (US) 2004-07-29 WO claimed
US-20030168629-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2003-09-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050287114-A1 Water-soluble polymeric bone-targeting drug delivery system HPGDS, CD44, BMP2 ACHE 4705/4885HDAC8 3357/4885TSHR 2851/4885
US-20260144617-A1 ORTHODONTIC CHEW, COMFORT TAPE, AND STICKER FOR THERAPEUTIC USE AND WOUND CARE SMCHD1, H1-2, H1-4 ACHE 157/4885HDAC8 9/4885TSHR 904/4885
US-20260061062-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM CD44, ALG1, HSF1 ACHE 2028/4885HDAC8 919/4885TSHR 2012/4885
US-20220008543-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM PLG, PYGL, PPIG ACHE 3459/4885HDAC8 714/4885TSHR 3110/4885
US-12600817-B2 Devices and methods for analyzing biological samples PGLS, HPSE, GALE ACHE 1696/4885HDAC8 1962/4885TSHR 1554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.