Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 19/20 | 0.49 |
| ▸ | WNT3 | P56703 | 6/20 | 0.49 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617253 | 0.82 | SFRP1 (0.72) | SFRP1WNT3 | |
| SCHEMBL4617230 | 0.70 | SFRP1 (0.63) | SFRP1WNT3 | |
| SCHEMBL16863987 | 0.67 | ALKBH2 (0.34) | ALKBH2ALKBH3FTO | |
| SCHEMBL4725927 | 0.67 | SFRP1 (0.77) | SFRP1WNT3 | |
| SCHEMBL4618018 | 0.66 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL2925179 | 0.66 | STS (0.62) | — | |
| Hydrochloric Acid SCHEMBL18248667 | 0.65 | SFRP1 (0.98) | SFRP1WNT3 | |
| SCHEMBL6102520 | 0.65 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL1817247 | 0.65 | POLB (0.61) | — | |
| SCHEMBL4616514 | 0.64 | SFRP1 (0.72) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |