Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 5/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462819 | 0.92 | NTRK1 (0.34) | OPRK1RETNR1H2NR1H3 | |
| SCHEMBL12064985 | 0.89 | DPP4 (0.33) | RETNR1H2 | |
| SCHEMBL463066 | 0.87 | NR1H2 (0.33) | OPRK1RETNR1H2NR1H3MAP3K5 | |
| SCHEMBL470535 | 0.85 | NR1H2 (0.33) | RETNR1H2MAP3K5 | |
| SCHEMBL470798 | 0.84 | DPP4 (0.32) | NR1H2 | |
| SCHEMBL12064592 | 0.83 | NR1H2 (0.31) | NR1H2 | |
| SCHEMBL470580 | 0.82 | NR1H2 (0.33) | OPRK1RETNR1H2MAP3K5 | |
| SCHEMBL12064983 | 0.82 | GPR119 (0.36) | NR1H2 | |
| SCHEMBL12064814 | 0.82 | NR1H2 (0.33) | RETNR1H2MAP3K5 | |
| SCHEMBL470523 | 0.81 | NTRK1 (0.35) | RETNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |