Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 19/20 | 0.51 |
| ▸ | WNT3 | P56703 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101888 | 0.83 | SFRP1 (0.46) | SFRP1WNT3MEN1KMT2A | |
| SCHEMBL4616993 | 0.83 | SFRP1 (0.62) | SFRP1WNT3 | |
| SCHEMBL4618051 | 0.83 | SFRP1 (0.65) | SFRP1WNT3 | |
| SCHEMBL16219423 | 0.80 | CTSB (0.55) | — | |
| SCHEMBL4733796 | 0.78 | MAPT (0.46) | MEN1KMT2A | |
| SCHEMBL4619410 | 0.74 | SFRP1 (0.57) | SFRP1WNT3 | |
| SCHEMBL4618344 | 0.74 | SFRP1 (0.72) | SFRP1WNT3 | |
| SCHEMBL4616152 | 0.74 | SFRP1 (0.60) | SFRP1WNT3 | |
| SCHEMBL4619287 | 0.72 | ALDH1A1 (0.58) | SFRP1WNT3MEN1KMT2A | |
| SCHEMBL4618174 | 0.72 | SFRP1 (0.55) | SFRP1WNT3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |