SCHEMBL4618271

SCHEMBL4618271

N#Cc1cccc(CO)c1CCCCO

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
POLB P06746 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
ESR2 Q92731 1/20 0.32
KDM1A O60341 1/20 0.32
KMT2A Q03164 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7396264 0.77 CYP19A1 (0.39) TSHRALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL16884620 0.77 GABRA1 (0.38) TSHRALDH1A1MAPTSMN1; SMN2CYP2C9
SCHEMBL16957400 0.75 S1PR1 (0.42) TSHRCYP2C9S1PR1
SCHEMBL3462088 0.75 FFAR1 (0.34) TSHRALDH1A1SMN1; SMN2KDM4ECA1
SCHEMBL6089703 0.75 CYP3A4 (0.42) TSHRALDH1A1MAPTKDM4ECYP1A2
SCHEMBL28046905 0.74 TSHR (0.38) TSHRALDH1A1SMN1; SMN2CYP2C9S1PR1
SCHEMBL15388928 0.73 ESR2 (0.42) TSHRALDH1A1KDM4ECA1CA2
SCHEMBL451478 0.73 CYP19A1 (0.41) TSHRALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL2134106 0.73 PDCD1 (0.48) TSHRALDH1A1MAPTSMN1; SMN2CA1
SCHEMBL30496165 0.72 ALDH1A1 (0.49) TSHRALDH1A1MAPTSMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1893766-A1 CHEMOENZYMATIC PROCESS FOR THE SYNTHESIS OF ESCITALOPRAM Adorkem Technology SpA (IT) 2008-03-05 EP disclosed
WO-2006136521-A1 CHEMOENZYMATIC PROCESS FOR THE SYNTHESIS OF ESCITALOPRAM ADORKEM TECHNOLOGY SPA (IT) 2006-12-28 WO disclosed