Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CASP4 | P49662 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | CASP9 | P55211 | 2/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758606 | 0.85 | RECQL (0.62) | RECQLL3MBTL1SCN2ANR1H2NR1H3 | |
| SCHEMBL16592564 | 0.85 | RECQL (0.62) | RECQLL3MBTL1SCN2ANR1H2NR1H3 | |
| SCHEMBL29895241 | 0.79 | CYP3A4 (0.56) | SCN2ANR1H2NR1H3ALDH1A1KMT2A | |
| SCHEMBL10915755 | 0.79 | CYP3A4 (0.56) | SCN2ANR1H2NR1H3ALDH1A1KMT2A | |
| SCHEMBL10885870 | 0.78 | RECQL (0.59) | RECQLL3MBTL1SCN2ANR1H2NR1H3 | |
| SCHEMBL6679920 | 0.78 | ALDH1A1 (0.52) | RECQLALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL11304554 | 0.77 | L3MBTL1 (0.74) | RECQLL3MBTL1SCN2ANR1H2NR1H3 | |
| SCHEMBL11872977 | 0.77 | NPC1 (0.59) | NR1H2NR1H3ALDH1A1KMT2AMAPT | |
| SCHEMBL20931235 | 0.76 | RPS6KA2 (0.45) | SCN2AALDH1A1KMT2ALMNARPS6KA2 | |
| SCHEMBL5924422 | 0.75 | SCN2A (0.58) | RECQLL3MBTL1SCN2ANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124452-B | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-115124452-A | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-115124452-B | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-115124452-B | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-115124452-A | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2022-09-30 | — | — | CN | disclosed |
| EP-1883621-A2 | METHODS OF PREPARING 3-CYANO-QUINOLINES AND INTERMEDIATES MADE THEREBY | Wyeth (US) | 2008-02-06 | — | — | EP | disclosed |
| US-20060270669-A1 | Method of preparing 3-cyano-quinolines and intermediates made thereby | WYETH | 2006-11-30 | — | — | US | disclosed |
| WO-2006127205-A2 | METHODS OF PREPARING 3-CYANO-QUINOLINES AND INTERMEDIATES MADE THEREBY | WYETH (US) | 2006-11-30 | — | — | WO | disclosed |
| US-4617316-A | Insecticidal heteroaryl substituted phenyl benzoylureas | FMC CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270669-A1 | Method of preparing 3-cyano-quinolines and intermediates made thereby | CNP, PPP4C, PTMS | RECQL 199/4885L3MBTL1 3799/4885SCN2A 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.