Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.57 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.57 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.57 |
| ▸ | PRKX | P51817 | 1/20 | 0.57 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.57 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.57 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956725 | 1.00 | MAPK1 (0.64) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL30289970 | 1.00 | MAPK1 (0.64) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL24453083 | 0.87 | MAPK1 (0.57) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL2973301 | 0.85 | MAPK1 (0.68) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL3897966 | 0.85 | MAPK1 (0.68) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL3959317 | 0.85 | MAPK1 (0.68) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL4330755 | 0.85 | MAPK1 (0.68) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL8837489 | 0.84 | CTRB1 (0.73) | CTRB1MME | |
| SCHEMBL5685800 | 0.84 | CTRB1 (0.73) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 | |
| SCHEMBL3682310 | 0.84 | CTRB1 (0.73) | MAPK1CYP3A4ROCK2ROCK1RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893291-A1 | TREATMENT OF SEXUAL DYSFUNCTION | SK Holdings Co., Ltd. (KR) | 2008-03-05 | — | — | EP | claimed |
| WO-2007001841-A1 | TREATMENT OF SEXUAL DYSFUNCTION | SK HOLDINGS CO., LTD. (KR) | 2007-01-04 | — | — | WO | claimed |
| US-20230242476-A1 | A PROCESS FOR THE PURIFICATION OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | FLAMMA SPA (IT) | 2023-08-03 | — | — | US | disclosed |
| US-20230242476-A1 | A PROCESS FOR THE PURIFICATION OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | FLAMMA SPA (IT) | 2023-08-03 | — | — | US | disclosed |
| US-11447448-B2 | Process for the preparation of solriamfetol and salt thereof | GLENMARK LIFE SCIENCES LIMITED (IN) | 2022-09-20 | — | — | US | disclosed |
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | ALIVUS LIFE SCIENCES LIMITED (IN) | 2022-05-26 | — | — | US | disclosed |
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | ALIVUS LIFE SCIENCES LIMITED (IN) | 2022-05-26 | — | — | US | disclosed |
| WO-2020035769-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK LIFE SCIENCES LIMITED (IN) | 2020-02-20 | — | — | WO | disclosed |
| EP-1890684-A1 | TREATMENT OF SLEEP-WAKE DISORDERS | SK Holdings Co., Ltd. (KR) | 2008-02-27 | — | — | EP | disclosed |
| EP-1819328-A1 | ADJUNCTIVE THERAPY FOR DEPRESSION | SK Corporation (KR) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006133393-A1 | TREATMENT OF SLEEP-WAKE DISORDERS | SK HOLDINGS CO., LTD. (KR) | 2006-12-14 | — | — | WO | disclosed |
| WO-2006050037-A1 | ADJUNCTIVE THERAPY FOR DEPRESSION | SK CORPORATION (KR) | 2006-05-11 | — | — | WO | disclosed |
| WO-1996024577-A1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1996-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | TST, SPR, STS | MAPK1 833/4885CYP3A4 3265/4885ROCK2 4066/4885 |
| US-11447448-B2 | Process for the preparation of solriamfetol and salt thereof | TST, SPR, STS | MAPK1 833/4885CYP3A4 3265/4885ROCK2 4066/4885 |
| US-20230242476-A1 | A PROCESS FOR THE PURIFICATION OF (R)-2-AMINO-3-PHENYLPROPYL CARBAMATE | PHYKPL, BPHL, DNPEP | MAPK1 3019/4885CYP3A4 1272/4885ROCK2 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.