Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CXCR5 | P32302 | 8/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728457 | 0.80 | CRBN (0.50) | ALDH1A1SMN1; SMN2P2RX7NPC1RAB9A | |
| SCHEMBL4781584 | 0.77 | P2RX7 (0.41) | ALDH1A1P2RX7NPC1CNR2 | |
| SCHEMBL19155146 | 0.75 | NPC1 (0.60) | ALDH1A1SMN1; SMN2P2RX7NPC1RAB9A | |
| SCHEMBL28474167 | 0.72 | RAB9A (0.70) | ALDH1A1SMN1; SMN2NPC1RAB9ATAS1R3 | |
| SCHEMBL7322497 | 0.72 | HDAC8 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9ACD44 | |
| SCHEMBL31038153 | 0.72 | PLK1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9ACD44 | |
| SCHEMBL635088 | 0.72 | PLK1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9ACD44 | |
| SCHEMBL28469392 | 0.71 | RAB9A (0.73) | ALDH1A1SMN1; SMN2NPC1RAB9ACNR2 | |
| SCHEMBL30080257 | 0.71 | RAB9A (0.73) | ALDH1A1SMN1; SMN2NPC1RAB9ACNR2 | |
| Hydrochloric Acid SCHEMBL31400038 | 0.71 | PLK1 (0.49) | ALDH1A1SMN1; SMN2NPC1RAB9ACD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031548-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031548-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031549-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031549-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| EP-1900730-A1 | Process for the preparation of anthranilamide derivatives | Syngeta Participations AG (CH) | 2008-03-19 | — | — | EP | disclosed |
| EP-1900730-A1 | Process for the preparation of anthranilamide derivatives | Syngeta Participations AG (CH) | 2008-03-19 | — | — | EP | disclosed |