Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620163 | 1.00 | PKLR (0.48) | PKLRCA2CA1MMEITGAV | |
| SCHEMBL4620012 | 1.00 | PKLR (0.48) | PKLRCA2CA1MMEITGAV | |
| SCHEMBL4620569 | 0.82 | CA2 (0.46) | CA2CA1MMP9MMP2MMP13 | |
| SCHEMBL4621422 | 0.82 | CA2 (0.46) | CA2CA1MMP9MMP2MMP13 | |
| SCHEMBL4621761 | 0.82 | CA2 (0.46) | CA2CA1MMP9MMP2MMP13 | |
| SCHEMBL4620281 | 0.81 | GPR139 (0.50) | ITGAVMMP2 | |
| SCHEMBL4621579 | 0.81 | GPR139 (0.50) | ITGAVMMP2 | |
| SCHEMBL4621602 | 0.81 | GPR139 (0.50) | ITGAVMMP2 | |
| SCHEMBL4621222 | 0.77 | NPC1 (0.46) | PKLRITGAV | |
| SCHEMBL4621354 | 0.77 | NPC1 (0.46) | PKLRITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |