Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | MMP2 | P08253 | 8/20 | 0.46 |
| ▸ | MMP13 | P45452 | 7/20 | 0.46 |
| ▸ | MMP3 | P08254 | 6/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621761 | 1.00 | CA2 (0.46) | CA2MMP2MMP13MMP3MMP1 | |
| SCHEMBL4621422 | 1.00 | CA2 (0.46) | CA2MMP2MMP13MMP3MMP1 | |
| SCHEMBL4620281 | 0.84 | GPR139 (0.50) | MMP2PARP1 | |
| SCHEMBL4621602 | 0.84 | GPR139 (0.50) | MMP2PARP1 | |
| SCHEMBL4621579 | 0.84 | GPR139 (0.50) | MMP2PARP1 | |
| SCHEMBL4620012 | 0.82 | PKLR (0.48) | CA2MMP2MMP13MMP9MMP8 | |
| SCHEMBL4620009 | 0.82 | PKLR (0.48) | CA2MMP2MMP13MMP9MMP8 | |
| SCHEMBL4620163 | 0.82 | PKLR (0.48) | CA2MMP2MMP13MMP9MMP8 | |
| SCHEMBL4622173 | 0.81 | CA1 (0.47) | CA2MMP2MMP13MMP3MMP1 | |
| SCHEMBL4620575 | 0.81 | CA1 (0.47) | CA2MMP2MMP13MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |