Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442002 | 0.84 | MAOA (0.45) | MAOAMAOBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL29049090 | 0.77 | CD69 (0.53) | MAOAMAOBMTNR1AMTNR1BCD69 | |
| SCHEMBL7150887 | 0.74 | ALOX5 (0.48) | MAOAMAOBPTGS2 | |
| SCHEMBL30586108 | 0.73 | GPR84 (0.45) | MAOAMAOBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL29049098 | 0.73 | MAOA (0.41) | MAOAMAOBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL6907494 | 0.72 | PTGS2 (0.41) | MAOAMAOBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL8031056 | 0.72 | PTGS2 (0.53) | MAOAMAOBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL17830823 | 0.72 | MAOA (0.40) | MAOAMAOBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL15058205 | 0.72 | MAOA (0.40) | MAOAMAOBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL28207332 | 0.72 | MAOA (0.40) | MAOAMAOBMTNR1AMTNR1BPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009127338-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |
| EP-0683435-B1 | Positive-working radiation-sensitive composition | AGFA GEVAERT AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0683435-A1 | Positive-working radiation-sensitive composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-22 | — | — | EP | disclosed |