1-Methylimidazole

1-Methylimidazole

SCHEMBL4620121

CCCCCCCCCCCCOS(=O)(=O)C(F)(F)C(F)F.Cn1ccnc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.38
NFKB1 P19838 1/20 0.36
QPCT Q16769 1/20 0.36
HSD17B10 Q99714 1/20 0.36
QPCTL Q9NXS2 1/20 0.36
CA1 P00915 9/20 0.34
CA2 P00918 9/20 0.34
CA9 Q16790 8/20 0.34
CA12 O43570 3/20 0.34
CA7 P43166 3/20 0.34
CA14 Q9ULX7 3/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
RECQL P46063 2/20 0.33
MAPK1 P28482 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Methylimidazole SCHEMBL16280485 0.88 TBXAS1 (0.41) TBXAS1NFKB1QPCTHSD17B10QPCTL
1-Methylimidazole SCHEMBL38665424 0.78 TBXAS1 (0.44) TBXAS1NFKB1QPCTHSD17B10QPCTL
1-Methylimidazole SCHEMBL5491564 0.78 TBXAS1 (0.44) TBXAS1NFKB1QPCTHSD17B10QPCTL
1-Methylimidazole SCHEMBL5015189 0.77 CYP3A4 (0.34) TBXAS1CYP3A4CYP2D6MAPK1TBXA2R
Amylosulfuric Acid SCHEMBL5482271 0.77 NFKB1 (0.44) TBXAS1NFKB1QPCTHSD17B10QPCTL
SCHEMBL4369370 0.76 CA2 (0.45) CA1CA2CA9CA12CA7
1-Methylimidazole SCHEMBL5015200 0.76 TBXA2R (0.33) TBXAS1CYP3A4CYP2D6MAPK1TBXA2R
1-Methylimidazole SCHEMBL15778945 0.74 QPCT (0.47) TBXAS1NFKB1QPCTHSD17B10QPCTL
Decane SCHEMBL28356613 0.72 QPCT (0.68) TBXAS1NFKB1QPCTHSD17B10QPCTL
Octane SCHEMBL28389156 0.72 QPCT (0.68) TBXAS1NFKB1QPCTHSD17B10QPCTL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1882132-A2 HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE E.I. du Pont de Nemours & Company (US) 2008-01-30 EP disclosed
WO-2006124776-A2 HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2006-11-23 WO disclosed