Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15778947 | 0.73 | TLR8 (0.37) | TLR8CHRNB2CHRNA4KDM4EHTT | |
| SCHEMBL2830180 | 0.70 | ALDH1A1 (0.46) | TLR8KDM4ELMNAMAPTHTT | |
| SCHEMBL3914898 | 0.69 | CHRNB2 (0.41) | CHRNB2CHRNA4KDM4ELMNAMAPT | |
| SCHEMBL5185067 | 0.68 | TLR8 (0.33) | TLR8KDM4ELMNAMAPTHTT | |
| SCHEMBL27841536 | 0.66 | CHRNB2 (0.40) | TLR8CHRNB2CHRNA4MAPTHTT | |
| SCHEMBL22951446 | 0.66 | TLR8 (0.36) | TLR8LMNAHTTALDH1A1POLB | |
| SCHEMBL459536 | 0.66 | CHRNB2 (0.40) | CHRNB2CHRNA4KDM4EHTTSMN1; SMN2 | |
| SCHEMBL2722061 | 0.66 | CHRNB2 (0.56) | TLR8CHRNB2CHRNA4ALDH1A1POLB | |
| SCHEMBL7643751 | 0.65 | CES2 (0.44) | KMT2A | |
| SCHEMBL1681801 | 0.65 | FPR2 (0.33) | MAPTSMN1; SMN2ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882132-A2 | HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE | E.I. du Pont de Nemours & Company (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006124776-A2 | HYBRID VAPOR COMPRESSION-ABSORPTION CYCLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-23 | — | — | WO | disclosed |