Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | DPP4 | P27487 | 7/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257752 | 0.73 | DPP4 (0.44) | GPR119DPP4DPP8 | |
| SCHEMBL462507 | 0.72 | GPR119 (0.50) | GPR119DPP4DPP8 | |
| SCHEMBL1092391 | 0.71 | GPR119 (0.67) | GPR119 | |
| SCHEMBL11957012 | 0.69 | GPR119 (0.57) | GPR119 | |
| SCHEMBL4259566 | 0.69 | CHRNA3 (0.53) | GPR119 | |
| SCHEMBL16758032 | 0.69 | CHRNB2 (0.51) | GPR119 | |
| SCHEMBL121270 | 0.68 | DPP4 (0.42) | GPR119DPP4DPP8 | |
| SCHEMBL121491 | 0.68 | GPR119 (0.41) | GPR119DPP4DPP8 | |
| SCHEMBL11957010 | 0.68 | GPR119 (0.49) | GPR119 | |
| SCHEMBL11956904 | 0.67 | GPR119 (0.54) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |