Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662204 | 0.88 | GPR119 (0.47) | GPR119KMT2ANAMPTCHRM2CHRM1 | |
| SCHEMBL3399260 | 0.86 | GPR119 (0.47) | GPR119KMT2AMEN1HRH3 | |
| SCHEMBL7390760 | 0.84 | LIPE (0.55) | GPR119KMT2APOLB | |
| SCHEMBL7396050 | 0.83 | KMT2A (0.50) | GPR119KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL865044 | 0.83 | GPR119 (0.56) | GPR119CCR5ALDH1A1CHRM2 | |
| SCHEMBL31112160 | 0.82 | HRH2 (0.49) | GPR119KMT2AMEN1GAACCR5 | |
| SCHEMBL2556476 | 0.81 | GPR119 (0.69) | GPR119CHRM2CHRM1 | |
| SCHEMBL2556948 | 0.81 | GPR119 (0.69) | GPR119CHRM2CHRM1 | |
| SCHEMBL2457230 | 0.81 | FAAH (0.51) | GPR119KMT2AMEN1CCR5ALDH1A1 | |
| SCHEMBL2460397 | 0.81 | POLB (0.47) | GPR119KMT2AMEN1GAACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883636-A1 | SUBSTITUTED PIPERIDINE ANTAGONIST OF HI RECEPTOR TO BE USED FOR THE TREATMENT OF RHINITIS | GLAXO GROUP LIMITED (GB) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006125665-A1 | SUBSTITUTED PIPERIDINE ANTAGONIST OF HI RECEPTOR TO BE USED FOR THE TREATMENT OF RHINITIS | GLAXO GROUP LIMITED (GB) | 2006-11-30 | — | — | WO | disclosed |