SCHEMBL462092

SCHEMBL462092

NC=CCN1CCOCC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KEAP1 Q14145 1/20 0.41
TSHR P16473 2/20 0.40
USP2 O75604 1/20 0.38
HSD17B10 Q99714 3/20 0.35
ALOX15 P16050 2/20 0.34
HTT P42858 1/20 0.34
ANPEP P15144 1/20 0.34
GLA P06280 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
CYP2C9 P11712 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
NCF1 P14598 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418109 1.00 KDM4E (0.41) KDM4EALDH1A1SMN1; SMN2KEAP1TSHR
SCHEMBL10748936 0.85 KDM4E (0.44) KDM4EALDH1A1SMN1; SMN2KEAP1TSHR
SCHEMBL10748084 0.85 KDM4E (0.44) KDM4EALDH1A1SMN1; SMN2KEAP1TSHR
SCHEMBL1464937 0.82 ALOX15 (0.32) ALOX15
SCHEMBL1464365 0.82 ALOX15 (0.32) ALOX15
SCHEMBL5140694 0.82
SCHEMBL23298992 0.79 SMN1; SMN2 (0.45) KDM4EALDH1A1SMN1; SMN2KEAP1TSHR
SCHEMBL21872268 0.78 KDM4E (0.41) KDM4EALDH1A1SMN1; SMN2KEAP1TSHR
SCHEMBL1169814 0.77
SCHEMBL6097541 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12031111-B2 Xylose carbamates as soil release agents HENKEL AG & CO. KGAA (DE) 2024-07-09 US claimed
US-20240074437-A1 SURFACE ANTIMICROBIAL TREATMENTS Crossing S.r.l. (IT) 2024-03-07 US claimed
EP-4258879-A1 SURFACE ANTIMICROBIAL TREATMENTS Crossing S.r.l. (IT) 2023-10-18 EP claimed
EP-3810742-B1 XYLOSE CARBAMATES AS SOIL RELEASE AGENTS HENKEL AG & CO KGAA (DE) 2022-08-03 EP claimed
WO-2022123441-A1 SURFACE ANTIMICROBIAL TREATMENTS Crossing S.r.l. (IT) 2022-06-16 WO claimed
EP-3810742-A1 XYLOSE CARBAMATES AS SOIL RELEASE AGENTS Henkel AG & Co. KGaA (DE) 2021-04-28 EP claimed
US-20210115358-A1 Xylose Carbamates As Soil Release Agents HENKEL AG & CO. KGAA (DE) 2021-04-22 US claimed
WO-2019243071-A1 XYLOSE CARBAMATES AS SOIL RELEASE AGENTS HENKEL AG & CO. KGAA (DE) 2019-12-26 WO claimed
EP-3049508-B1 CELLULOSE CARBAMATE AS SOIL RELEASE AGENT HENKEL AG & CO KGAA (DE) 2018-03-28 EP claimed
EP-1099718-B1 Tertiary amine-containing active methylene compounds for improving the dimensional stability of polyurethane foam AIR PROD & CHEM (US) 2005-03-30 EP claimed
US-6248801-B1 CELL OPENING ADJUVANTS AIR PRODUCTS AND CHEMICALS, INC. 2001-06-19 US claimed
EP-1099718-A2 Tertiary amine-containing active methylene compounds for improving the dimensional stability of polyurethane foam AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-05-16 EP claimed
US-4357250-A DIENE-ETHYLENE-PROPYLENE TERPOLYMER, UNSATURATED ACID, AMINE THE LUBRIZOL CORPORATION (US) 1982-11-02 US claimed
US-4320019-A Multi-purpose additive compositions and concentrates containing same THE LUBRIZOL CORPORATION (US) 1982-03-16 US claimed
US-4292185-A COMPRISING A DIENE-MODIFIED MONOOLEFINIC POLYMER REACTED WITH CHLOROSULFONYL ISOCYANATE AND THEN WITH AN AMINE ROHM AND HAAS COMPANY (US) 1981-09-29 US claimed
US-12031111-B2 Xylose carbamates as soil release agents HENKEL AG & CO. KGAA (DE) 2024-07-09 US disclosed
US-11912877-B2 Aluminum-based coupling agents BRANT PATRICK (US) 2024-02-27 US disclosed
US-4258042-A Antihypertensive pyridines and compositions USV PHARMACEUTICAL CORPORATION (US) 1981-03-24 US disclosed
US-4234435-A Novel carboxylic acid acylating agents, derivatives thereof, concentrate and lubricant compositions containing the same, and processes for their preparation THE LUBRIZOL CORPORATION (US) 1980-11-18 US disclosed
US-3957492-A Photographic silver halide emulsion comprising an amphoteric copolymer FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074437-A1 SURFACE ANTIMICROBIAL TREATMENTS CUTA, ETF1, SFN KDM4E 3012/4885ALDH1A1 3255/4885SMN1; SMN2 4615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.