Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621745 | 1.00 | MMP13 (0.54) | MMP13MMP8MMP12LDHAKMT2A | |
| SCHEMBL4621737 | 0.85 | AKR1C3 (0.47) | KMT2ACA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4621513 | 0.85 | AKR1C3 (0.47) | KMT2ACA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4620988 | 0.85 | AKR1C3 (0.47) | KMT2ACA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4620781 | 0.84 | MMP8 (0.56) | MMP13MMP8MMP12LDHAKMT2A | |
| SCHEMBL4621111 | 0.84 | MMP8 (0.56) | MMP13MMP8MMP12LDHAKMT2A | |
| SCHEMBL4620227 | 0.84 | MMP8 (0.56) | MMP13MMP8MMP12LDHAKMT2A | |
| SCHEMBL4619148 | 0.83 | MMP12 (0.50) | MMP13MMP8MMP12ITGB3ITGA2B | |
| SCHEMBL4623983 | 0.83 | MMP12 (0.50) | MMP13MMP8MMP12ITGB3ITGA2B | |
| SCHEMBL4621584 | 0.83 | MMP12 (0.50) | MMP13MMP8MMP12ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |