Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | FGF1 | P05230 | 2/20 | 0.40 |
| ▸ | FGF2 | P09038 | 2/20 | 0.40 |
| ▸ | VEGFA | P15692 | 2/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335356 | 1.00 | TSHR (0.44) | TSHRIDO1PDPK1MTORFGF1 | |
| SCHEMBL7775231 | 0.82 | PDPK1 (0.45) | TSHRPDPK1MTORFGF1FGF2 | |
| SCHEMBL24378456 | 0.82 | PDPK1 (0.47) | TSHRIDO1PDPK1MTORAGXT | |
| SCHEMBL7133576 | 0.81 | SLC5A2 (0.45) | MAPTMAPK1 | |
| SCHEMBL20643537 | 0.81 | SLC5A2 (0.45) | MAPTMAPK1 | |
| SCHEMBL15671094 | 0.81 | SLC5A2 (0.45) | MAPTMAPK1 | |
| SCHEMBL3642166 | 0.81 | SLC5A2 (0.45) | MAPTMAPK1 | |
| SCHEMBL7154852 | 0.81 | SLC5A2 (0.45) | MAPTMAPK1 | |
| SCHEMBL18573748 | 0.80 | PDPK1 (0.50) | TSHRIDO1PDPK1MTORAGXT | |
| SCHEMBL29524151 | 0.80 | TK1 (0.41) | IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702165-A | Method for preparing cyclic carbonate by taking NHC/ZnBr2 system as catalyst | UNIV JIANGSU NORMAL | 2012-10-03 | — | — | CN | disclosed |
| US-20080213833-A1 | Methods for Obtaining Optically Active Glycidyl Ethers and Optically Active Vicinal Diols from Racemic Substrates | OXRANE (UK) LTD. (GB) | 2008-09-04 | — | — | US | disclosed |
| EP-1885849-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | Oxyrane UK Limited (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006109198-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | OXYRANE UK LIMITED (GB) | 2006-10-19 | — | — | WO | disclosed |
| US-20060105047-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2006-05-18 | — | — | US | disclosed |
| US-20050100579-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2005-05-12 | — | — | US | disclosed |
| US-6858218-B2 | Hydrogel from polysiloxane-containing urethane prepolymer, tris (trimethylsiloxy) silylpropyl methacrylate, and a hydrophilic comonomer | BAUSCH & LOMB INCORPORATED (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030157141-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2003-08-21 | — | — | US | disclosed |
| US-6596294-B2 | Oxygen permeability and superior physical properties, contact lenses | BAUSCH & LOMB INCORPORATED | 2003-07-22 | — | — | US | disclosed |
| US-20020037271-A1 | Novel prepolymers useful in biomedical devices | BAUSCH & LOMB INCORPORATED | 2002-03-28 | — | — | US | disclosed |
| EP-0330615-A2 | Wettable, flexible, oxygen permeable, contact lens containing polyoxyalkylene backbone units, and use thereof | CIBA-GEIGY AG (CH) | 1989-08-30 | — | — | EP | disclosed |
| EP-0330617-A1 | Wettable, flexible, oxygen permeable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units | CIBA-GEIGY AG (CH) | 1989-08-30 | — | — | EP | disclosed |
| US-4857606-A | Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing polyoxyalkylene backbone units, and use thereof | CIGA-GEIGY CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4780488-A | INTRAOCULAR LENSES | CIBA-GEIGY CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0267158-A1 | Substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units | CIBA-GEIGY AG (CH) | 1988-05-11 | — | — | EP | disclosed |
| US-4740533-A | Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof | CIBA-GEIGY CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0263061-A2 | Substantially non-swellable contact lens containing polyoxyalkylene backbone units | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| US-4256900-A | Fluorescent azolyl benzocoumarin dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4233214-A | FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4036826-A | Cationic azo dyestuffs with a hydroxyalkylated ammonium group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037271-A1 | Novel prepolymers useful in biomedical devices | TMEM63A, ECPAS, COL2A1 | TSHR 4883/4885IDO1 3389/4885PDPK1 3504/4885 |
| US-20080213833-A1 | Methods for Obtaining Optically Active Glycidyl Ethers and Optically Active Vicinal Diols from Racemic Substrates | GALE, DERA, GNE | TSHR 4775/4885IDO1 1550/4885PDPK1 4476/4885 |
| US-20060105047-A1 | Novel prepolymers useful in biomedical devices | TMEM63A, ECPAS, COL2A1 | TSHR 4883/4885IDO1 3389/4885PDPK1 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.