Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621254 | 1.00 | L3MBTL1 (0.57) | L3MBTL1APPKDM4ENPC1JUN | |
| SCHEMBL27224514 | 0.95 | LMNA (0.59) | L3MBTL1APPKDM4ENPC1JUN | |
| SCHEMBL27397301 | 0.95 | LMNA (0.59) | L3MBTL1APPKDM4ENPC1JUN | |
| SCHEMBL533791 | 0.86 | RAB9A (0.61) | L3MBTL1KDM4ENPC1JUNMAPT | |
| SCHEMBL30012000 | 0.86 | RAB9A (0.61) | L3MBTL1KDM4ENPC1JUNMAPT | |
| SCHEMBL13957158 | 0.86 | RAB9A (0.61) | L3MBTL1KDM4ENPC1JUNMAPT | |
| SCHEMBL533790 | 0.86 | RAB9A (0.61) | L3MBTL1KDM4ENPC1JUNMAPT | |
| SCHEMBL30930826 | 0.86 | RAB9A (0.61) | L3MBTL1KDM4ENPC1JUNMAPT | |
| SCHEMBL27866402 | 0.83 | APP (0.58) | APPMAPTRAB9ALMNAATM | |
| SCHEMBL10054822 | 0.83 | APP (0.58) | APPMAPTRAB9ALMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014074715-A1 | CYCLOPROPYL AMIDE DERIVATIVES | GENENTECH, INC. (US) | 2014-05-15 | — | — | WO | disclosed |
| EP-1368287-B1 | PROCESS FOR A HOMOGENEOUSLY CATALYZED C-C COUPLING REACTION | DSM IP ASSETS BV (NL) | 2008-03-26 | — | — | EP | disclosed |
| US-6784295-B2 | CARRIED OUT IN THE PRESENCE OF AN INORGANIC BASE OR ORGANIC NITROGEN BASE AND A PALLADIUM COMPLEX CATALYST CONTAINING SECONDARY MONOPHOSPHINES WITH ALIPHATIC, BRANCHED OR CYCLIC SUBSTITUENTS AS LIGANDS | SOLVIAS AG (CH) | 2004-08-31 | — | — | US | disclosed |
| EP-1132361-B1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | SOLVIAS AG (CH) | 2003-05-14 | — | — | EP | disclosed |