SCHEMBL533791

SCHEMBL533791

CCOC(=O)C=Cc1cccnc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.61
NPC1 O15118 3/20 0.61
MAPT P10636 2/20 0.61
KDM4E B2RXH2 2/20 0.61
JUN P05412 1/20 0.61
NFKB1 P19838 1/20 0.61
MAPK1 P28482 1/20 0.61
GPR55 Q9Y2T6 1/20 0.61
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
PFKFB3 Q16875 1/20 0.54
CYP1A1 P04798 6/20 0.53
CYP1A2 P05177 6/20 0.53
CYP1B1 Q16678 6/20 0.53
TTR P02766 1/20 0.52
DPP4 P27487 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL533790 1.00 RAB9A (0.61) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL30930826 1.00 RAB9A (0.61) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL30012000 1.00 RAB9A (0.61) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL13957158 1.00 RAB9A (0.61) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL5962608 0.90 RAB9A (0.53) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL5962606 0.90 RAB9A (0.53) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL4621246 0.86 L3MBTL1 (0.57) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL4621254 0.86 L3MBTL1 (0.57) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL21959852 0.85 TTR (0.51) RAB9ANPC1MAPTKDM4EJUN
SCHEMBL8133474 0.84 MAPT (0.47) RAB9ANPC1MAPTKDM4EJUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708027-A Method for preparing boronated carbonyl derivative 中国科学院大连化学物理研究所 2025-03-28 CN claimed
US-11993595-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2024-05-28 US disclosed
US-20230052191-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2023-02-16 US disclosed
US-11472798-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2022-10-18 US disclosed
CN-107674013-B Polycyclic compound, preparation method, pharmaceutical composition and application thereof 上海迪诺医药科技有限公司 2022-05-24 CN disclosed
EP-3828179-A1 CYANOPYRROLIDINES AS DUB MODULATORS Mission Therapeutics Limited (GB) 2021-06-02 EP disclosed
US-20200369658-A1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2020-11-26 US disclosed
US-10774078-B2 Compounds MISSION THERAPEUTICS LTD (GB) 2020-09-15 US disclosed
CN-111592534-A Novel compounds 特殊治疗有限公司 2020-08-28 CN disclosed
EP-3197883-B1 NOVEL COMPOUNDS MISSION THERAPEUTICS LTD (GB) 2020-03-18 EP disclosed
US-5378727-A ADMINISTERING TO MAMMALS G. D. SEARLE & CO. (US) 1995-01-03 US disclosed
EP-0630366-A1 SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. Searle & Co. (US) 1994-12-28 EP disclosed
US-5371096-A (3-pyridyl)tetrafuran-2-yl substituted carboxylic acids CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
US-5254573-A Substituted heterocyclic derivatives useful as platelet aggregation inhibitors MONSANTO COMPANY (US) 1993-10-19 US disclosed
EP-0284395-B1 NOVEL GLYCEROL DERIVATIVE AND ANTI-HYPERTENSIVE AGENT NIPPON CHEMIPHAR CO., LTD. (JP) 1993-06-23 EP disclosed
WO-1993008164-A1 SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1993-04-29 WO disclosed
EP-0539343-A1 Substituted heterocyclic derivatives useful as platelet aggregation inhibitors MONSANTO COMPANY (US) 1993-04-28 EP disclosed
US-5183811-A Glycerol derivative and anti-hypertensive agent NIPPON CHEMIPHAR CO., LTD. (JP) 1993-02-02 US disclosed
US-4962096-A WITH REDUCED PLATELET AGGREGATING ACTION NIPPON CHEMIPHAR CO., LTD. (JP) 1990-10-09 US disclosed
EP-0284395-A2 Novel glycerol derivative and anti-hypertensive agent NIPPON CHEMIPHAR CO., LTD. (JP) 1988-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10774078-B2 Compounds UCHL1, UCHL3, UCHL5 RAB9A 519/4885NPC1 2436/4885MAPT 2227/4885
US-11472798-B2 Compounds UCHL1, UCHL3, UCHL5 RAB9A 519/4885NPC1 2436/4885MAPT 2227/4885
US-11993595-B2 Compounds UCHL1, UCHL3, UCHL5 RAB9A 519/4885NPC1 2436/4885MAPT 2227/4885
US-20200369658-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 RAB9A 480/4885NPC1 2546/4885MAPT 2428/4885
US-20230052191-A1 NOVEL COMPOUNDS UCHL1, UCHL3, UCHL5 RAB9A 480/4885NPC1 2546/4885MAPT 2428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.