SCHEMBL4621374

SCHEMBL4621374

Cc1cn([C@H]2CC[C@@H](CO)O2)c(=S)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
ALB P02768 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 1/20 0.46
BLM P54132 2/20 0.46
POLB P06746 1/20 0.46
ADRA1A P35348 1/20 0.46
TK1 P04183 4/20 0.45
TSHR P16473 2/20 0.45
PKM P14618 1/20 0.45
PMP22 Q01453 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21277447 0.90 TK1 (0.43) LMNAALBALDH1A1BLMPOLB
SCHEMBL21277437 0.90 TK1 (0.43) LMNAALBALDH1A1BLMPOLB
SCHEMBL925743 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB
SCHEMBL14596607 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB
SCHEMBL14421795 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB
SCHEMBL23485 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB
SCHEMBL22992337 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB
SCHEMBL762579 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB
SCHEMBL13286394 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB
SCHEMBL29711774 0.86 LMNA (0.58) LMNAALBALDH1A1BLMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262186-A2 THERAPEUTIC OLIGONUCLEOTIDES FOR TREATING DISEASES BEING ASSOCIATED WITH OR CAUSED BY A MISSENSE, NONSENSE OR IN-FRAME INDEL MUTATION MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-12-26 WO claimed
WO-2025069117-A1 METHOD FOR HIGHLY SENSITIVE ANALYTES DETECTION ULISSE BIOMED S.P.A. (IT) 2025-04-03 WO claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
EP-3452601-B1 CELL-FREE PROTEIN EXPRESSION USING ROLLING CIRCLE AMPLIFICATION PRODUCT Global Life Sciences Solutions Operations UK Ltd (GB) 2024-10-16 EP claimed
EP-3684934-B1 IN VIVO RNA OR PROTEIN EXPRESSION USING DOUBLE-STRANDED CONCATEMERIC DNA INCLUDING PHOSPHOROTHIOATED NUCLEOTIDES Global Life Sciences Solutions Operations UK Ltd (GB) 2024-06-19 EP claimed
CN-111094574-B In vivo RNA or protein expression using double stranded concatemer DNA comprising phosphorothioated nucleotides 环球生命科学解决方案运营英国有限公司 2024-04-16 CN claimed
CN-110997922-B Cell-free protein expression using double-stranded concatemer DNA 环球生命科学解决方案运营英国有限公司 2024-04-16 CN claimed
EP-3371326-B1 LIGASE-ASSISTED NUCLEIC ACID CIRCULARIZATION AND AMPLIFICATION Global Life Sciences Solutions Operations UK Ltd (GB) 2023-11-01 EP claimed
EP-3665286-B1 CELL-FREE PROTEIN EXPRESSION USING DOUBLE-STRANDED CONCATAMERIC DNA Global Life Sciences Solutions Operations UK Ltd (GB) 2023-09-13 EP claimed
US-20220389473-A1 CELL-FREE PROTEIN EXPRESSION USING ROLLING CIRCLE AMPLIFICATION PRODUCT GLOBAL LIFE SCIENCES SOLUTIONS OPERATIONS UK LIMITED (GB) 2022-12-08 US claimed
US-20170121747-A1 ISOTHERMAL AMPLIFICATION UNDER LOW SALT CONDITION Global Life Sciences Solutions Operations UK Ltd (GB) 2017-05-04 US claimed
US-9587263-B2 Isothermal amplification under low salt condition GENERAL ELECTRIC COMPANY (US) 2017-03-07 US claimed
EP-3122888-A2 ISOTHERMAL AMPLIFICATION UNDER LOW SALT CONDITION General Electric Company (US) 2017-02-01 EP claimed
US-9353393-B2 Methods and kits for reducing non-specific nucleic acid amplification GENERAL ELECTRIC COMPANY (US) 2016-05-31 US claimed
US-20160053307-A1 LIGASE-ASSISTED NUCLEIC ACID CIRCULARIZATION AND AMPLIFICATION Global Life Sciences Solutions Operations UK Ltd (GB) 2016-02-25 US claimed
WO-2015148218-A2 ISOTHERMAL AMPLIFICATION UNDER LOW SALT CONDITION GENERAL ELECTRIC COMPANY (US) 2015-10-01 WO claimed
US-20150275282-A1 ISOTHERMAL AMPLIFICATION UNDER LOW SALT CONDITION GENERAL ELECTRIC COMPANY (US) 2015-10-01 US claimed
EP-2814976-A1 METHODS AND KITS FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION General Electric Company (US) 2014-12-24 EP claimed
WO-2013123187-A1 METHODS AND KITS FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION GENERAL ELECTRIC COMPANY (US) 2013-08-22 WO claimed
US-20130210078-A1 METHODS AND KITS FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION GENERAL ELECTRIC COMPANY (US) 2013-08-15 US claimed