SCHEMBL462175

SCHEMBL462175

C(=Cc1ccccc1)C1=CCC(c2ccccc2)(c2nc3ccccc3o2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
HTT P42858 1/20 0.36
SNCA P37840 1/20 0.34
ELANE P08246 1/20 0.33
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
NPC1 O15118 4/20 0.32
RAB9A P51151 4/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.32
KDM1A O60341 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5966152 0.94 KMT2A (0.38) LMNAGAAMAPTKMT2AKDM4E
SCHEMBL25251301 0.85 NPC1 (0.39) LMNAGAAMAPTKMT2AKDM4E
SCHEMBL3959142 0.85 UTRN (0.31) MAPTKDM4EPOLBRAB9AL3MBTL1
SCHEMBL10881625 0.85 TRPV1 (0.33) MAPTKDM4EPOLBNPC1RAB9A
SCHEMBL444066 0.81 PSMB5 (0.33)
SCHEMBL6666383 0.81 NUDT1 (0.33) MAPTKDM4EPOLBNPC1RAB9A
SCHEMBL29739844 0.81 NPC1 (0.41) LMNAGAAMAPTKMT2AKDM4E
SCHEMBL296615 0.81 NPC1 (0.41) LMNAGAAMAPTKMT2AKDM4E
SCHEMBL5189265 0.81 CHAT (0.34) MAPTKMT2ANPC1RAB9AMEN1
SCHEMBL11391951 0.78 SNCA (0.34) LMNAGAAMAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240189217-A1 SUNSCREEN COMPOSITION INCLUDING A FLUORESCENT AGENT EXCITABLE BY AN ULTRAVIOLET LAM SHULMAN ZACHARY (US) 2024-06-13 US claimed
US-20190294069-A1 SECURITY LIQUID ELECTROSTATIC INK COMPOSITION HEWLETT-PACKARD INDIGO B.V. (NL) 2019-09-26 US claimed
EP-1610954-B1 METHOD FOR RECORDING INFORMATION IN LUMINESCENT COMPOSITIONS AND USES THEREOF IN ARTICLES OF MANUFACTURE AMERICAN DYE SOURCE INC (CA) 2010-11-17 EP claimed
US-7422649-B2 Method for recording information in luminescent compositions and uses thereof in articles of manufacture AMERICAN DYE SOURCE, INC. (CA) 2008-09-09 US claimed
US-7306809-B2 Optically activated particles for use in cosmetic compositions LIPO CHEMICALS, INC. (US) 2007-12-11 US claimed
US-20070258912-A1 Use of Fluorescent Whitening Agents as Antimicrobials CIBA SPECIALTY CHEMICALS CORP. 2007-11-08 US claimed
EP-1776086-A2 USE OF FLUORESCENT WHITENING AGENTS AS ANTIMICROBIALS Ciba Specialty Chemicals Holding Inc. (CH) 2007-04-25 EP claimed
EP-1545433-B1 OPTICALLY ACTIVATED PARTICLES FOR USE IN COSMETIC COMPOSITIONS LIPO CHEMICALS INC (US) 2007-01-17 EP claimed
EP-1610954-A4 METHOD FOR RECORDING INFORMATION IN LUMINESCENT COMPOSITIONS AND USES THEREOF IN ARTICLES OF MANUFACTURE AMERICAN DYE SOURCE INC (CA) 2006-09-13 EP claimed
WO-2006015959-A2 USE OF FLUORESCENT WHITENING AGENTS AS ANTIMICROBIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-16 WO claimed
EP-1099137-A4 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEM CO (US) 2004-10-06 EP claimed
WO-2004024103-A1 OPTICALLY ACTIVATED PARTICLES FOR USE IN COSMETIC COMPOSITIONS LIPO CHEMICALS, INC. (US) 2004-03-25 WO claimed
US-20040052742-A1 Optically activated particles for use in cosmetic compositions VANTAGE SPECIALTIES, INC. 2004-03-18 US claimed
US-20020136912-A1 NON-EXUDING OPTICALLY BRIGHTENED POLYOLEFIN BLENDS EASTMAN CHEMICAL COMPANY 2002-09-26 US claimed
EP-1240246-A1 NON-EXUDING OPTICALLY BRIGHTENED POLYOLEFIN BLENDS EASTMAN CHEMICAL COMPANY (US) 2002-09-18 EP claimed
US-6312822-B1 AS POLAR ADDITIVES POLYMERIC ESTERS, OLIGOMERIC ESTERS, POLYAMIDES, FATTY ACIDS AMIDES OF ALIPHATIC AMINES AND DIAMINES, COPOLYMERS OF POLY(ETHYLENE-COACRYLIC ACID), OR ESTERS OF POLY(ALKYLENE GLYCOLS) EASTMAN CHEM CO (US) 2001-11-06 US claimed
WO-2001036533-A1 NON-EXUDING OPTICALLY BRIGHTENED POLYOLEFIN BLENDS EASTMAN CHEMICAL COMPANY (US) 2001-05-25 WO claimed
EP-1099137-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2001-05-16 EP claimed
WO-1999061955-A1 DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 1999-12-02 WO claimed
US-5985389-A POLESTER OR POLYAMIDEESTER ACETALDEHYDE REDUCING COMPOUND; FOOD AND BEVERAGE CONTAINERS; CLARITY EASTMAN CHEMICAL COMPANY (US) 1999-11-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040052742-A1 Optically activated particles for use in cosmetic compositions CUTA, PLOD3, FIBP LMNA 136/4885GAA 504/4885MAPT 2038/4885
US-20070258912-A1 Use of Fluorescent Whitening Agents as Antimicrobials CUTA, CAT, LPO LMNA 421/4885GAA 544/4885MAPT 943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.