Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097047 | 0.94 | ALDH1A1 (0.32) | ALDH1A1GSTP1IDO1 | |
| SCHEMBL25277740 | 0.94 | ALDH1A1 (0.34) | ALDH1A1GSTP1IDO1 | |
| SCHEMBL4621793 | 0.84 | ALDH1A1 (0.45) | ALDH1A1GSTP1 | |
| SCHEMBL23818791 | 0.83 | TSHR (0.36) | ALDH1A1GSTP1IDO1 | |
| SCHEMBL20394083 | 0.83 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL1059386 | 0.83 | CA2 (0.32) | ALDH1A1IDO1 | |
| SCHEMBL20394068 | 0.83 | CA2 (0.32) | ALDH1A1IDO1 | |
| SCHEMBL130438 | 0.83 | APLNR (0.33) | — | |
| SCHEMBL14511263 | 0.82 | APLNR (0.36) | ALDH1A1IDO1 | |
| SCHEMBL133350 | 0.82 | APLNR (0.36) | ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334109-B1 | IMPROVED SYNTHESIS OF PURINE LOCKED NUCLEIC ACID ANALOGUES | SANTARIS PHARMA AS (DK) | 2006-05-10 | — | — | EP | disclosed |
| US-6998484-B2 | Synthesis of purine locked nucleic acid analogues | SANTARIS PHARMA A/S (DK) | 2006-02-14 | — | — | US | disclosed |
| US-20020086998-A1 | Synthesis of purine locked nucleic acid analogues | SANTARIS PHARMA A/S (DK) | 2002-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086998-A1 | Synthesis of purine locked nucleic acid analogues | RNGTT, PNP, UNG | ALDH1A1 1637/4885GSTP1 3174/4885IDO1 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.