Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16496359 | 0.80 | GAA (0.41) | ALDH1A1NOTUMFABP4KDM4EL3MBTL1 | |
| SCHEMBL2473118 | 0.80 | GAA (0.41) | ALDH1A1NOTUMFABP4KDM4EL3MBTL1 | |
| SCHEMBL29473859 | 0.79 | HTR6 (0.50) | NOTUMALOX15KDM4EKDM4AEGLN1 | |
| SCHEMBL16056407 | 0.79 | HTR6 (0.50) | NOTUMALOX15KDM4EKDM4AEGLN1 | |
| SCHEMBL3166303 | 0.78 | L3MBTL1 (0.43) | NOTUMFABP4L3MBTL1PTPN1FABP3 | |
| SCHEMBL1586669 | 0.78 | ALDH1A1 (0.41) | ALDH1A1NR4A1NR4A2NR4A3NOTUM | |
| SCHEMBL15018177 | 0.78 | NOTUM (0.72) | ALDH1A1NOTUML3MBTL1RAB9ATSHR | |
| SCHEMBL15512719 | 0.78 | NOTUM (0.45) | ALDH1A1NOTUMKDM4EL3MBTL1RAB9A | |
| SCHEMBL5623181 | 0.78 | FABP4 (0.48) | NOTUMFABP4L3MBTL1RAB9ATSHR | |
| SCHEMBL1130987 | 0.78 | PTPN1 (0.61) | ALDH1A1NR4A1NR4A2NR4A3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3612520-A1 | AN ISOXAZOLE DERIVATIVES AS NUCLEAR RECEPTOR AGONISTS AND USED THEREOF | Il Dong Pharmaceutical Co., Ltd. (KR) | 2020-02-26 | — | — | EP | disclosed |
| WO-2018190643-A1 | AN ISOXAZOLE DERIVATIVES AS NUCLEAR RECEPTOR AGONISTS AND USED THEREOF | IL DONG PHARMACEUTICAL CO., LTD. (KR) | 2018-10-18 | — | — | WO | disclosed |
| EP-1067950-B1 | NEO-TRYPTOPHAN | MAYO FOUNDATION (US) | 2008-05-14 | — | — | EP | disclosed |