SCHEMBL46223

SCHEMBL46223

CN1C(=O)C2=C(CCCC2)C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
TSHR P16473 1/20 0.38
BRD4 O60885 1/20 0.36
BRD2 P25440 1/20 0.36
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
TRIM24 O15164 2/20 0.35
TRIM33 Q9UPN9 2/20 0.35
MEN1 O00255 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PORCN Q9H237 2/20 0.32
CASP3 P42574 1/20 0.31
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30
MGLL Q99685 1/20 0.30
PLK1 P53350 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12406684 0.94 BRD4 (0.36) ALDH1A1MAPTTSHRBRD4BRD2
SCHEMBL14806789 0.83 ALDH1A1 (0.32) ALDH1A1MAPTTSHRBRD4BRD2
SCHEMBL13256285 0.78 BRD4 (0.30) BRD4BRD2
SCHEMBL11792246 0.74 ALDH1A1 (0.38) ALDH1A1MAPTTSHRBRD4BRD2
SCHEMBL24668614 0.74 CRBN (0.32)
SCHEMBL16835859 0.73 OR51E2 (0.38) ALDH1A1MAPTLMNAMEN1ALOX15
SCHEMBL17168147 0.71 CASP3 (0.31) KDM4ECASP3GSK3AGSK3BMGLL
SCHEMBL21449883 0.71 KDM4E (0.35) ALDH1A1KDM4ELMNATRIM24TRIM33
SCHEMBL585884 0.71 KDM4E (0.35) ALDH1A1KDM4ELMNATRIM24TRIM33
SCHEMBL14377617 0.71 KDM4E (0.35) ALDH1A1KDM4ELMNATRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230247992-A1 ARTHROPOD CONTROL COMPOSITION FIRMENICH & CIE (CH) 2023-08-10 US claimed
US-20220142157-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH SA (CH) 2022-05-12 US claimed
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
EP-2325385-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF SE (DE) 2011-05-25 EP claimed
US-7793920-B2 barrier against insect; the net structure made of polymer fibers is impregnated with an insecticide; preventing the low flying insects from entering open-air area; black color; invisible to certain insects VESTERGAARD SA (CH) 2010-09-14 US claimed
US-7503675-B2 Combination light device with insect control ingredient emission S.C. JOHNSON & SON, INC. (US) 2009-03-17 US claimed
WO-2008085363-A1 COMBINATION LIGHT DEVICE WITH INSECT CONTROL INGREDIENT EMISSION S. C. JOHNSON & SON, INC. (US) 2008-07-17 WO claimed
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
US-20070133206-A1 Combination Light Device with Insect Control Ingredient Emission S.C. JOHNSON AND SON, INC. (US) 2007-06-14 US claimed
US-4950682-A Arthropodicidal compositions CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1990-08-21 US claimed
EP-0364116-A1 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-18 EP claimed
US-4883806-A ACARICIDES ROUSSEL UCLAF (FR) 1989-11-28 US claimed
EP-0295839-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-21 EP claimed
US-4762835-A INSECTICIDES, MITICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-09 US claimed
EP-0227415-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-07-01 EP claimed
EP-0041021-B1 CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AGAINST PARASITES IN PLANTS AND ANIMALS, THEIR COMPOSITIONS AND THEIR INTERMEDIATES ROUSSEL-UCLAF (FR) 1984-07-25 EP claimed
EP-0011893-B1 PESTICIDAL COMPOSITION AND METHOD OF COMBATING PESTS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-06-09 EP claimed
EP-0011893-A1 Pesticidal composition and method of combating pests SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-06-11 EP claimed
US-4000266-A (1-CYCLOHEXENE-1,2-DICARBOXAMIDO)METHYL CHRYSANTHEMUMATE, (5-BENZYL-3-FURYL)METHYL CHRYSANTHEMUMATE FMC CORPORATION (US) 1976-12-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070196412-A1 Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests GAP43, GRN, DDT ALDH1A1 3986/4885MAPT 49/4885TSHR 152/4885
US-20220142157-A1 ARTHROPOD CONTROLLING COMPOSITION AGO2, NOP2, FBL ALDH1A1 3272/4885MAPT 2538/4885TSHR 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.