Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.65 |
| ▸ | ARG2 | P78540 | 4/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL273053 | 1.00 | GSR (0.65) | GSRARG2ARG1NOS2NOS1 | |
| Ornithine Aketoglutarate SCHEMBL272917 | 0.95 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| Ornithine SCHEMBL1539161 | 0.95 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28694100 | 0.86 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28694097 | 0.86 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL27799650 | 0.84 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL27799649 | 0.84 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Carnitine SCHEMBL9901519 | 0.83 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| Levocarnitine SCHEMBL6553881 | 0.83 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| Carnitine SCHEMBL9128766 | 0.83 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1152661-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2001-11-14 | — | — | EP | claimed |
| WO-2000047046-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2000-08-17 | — | — | WO | claimed |
| CN-108676106-B | Method for extracting polysaccharide and betaine from seaweed | 五邑大学 | 2021-01-12 | — | — | CN | disclosed |
| US-20080200533-A1 | Drug or Pharmaceutical Compounds and a Preparation Thereof | KRISHNAN RAMU | 2008-08-21 | — | — | US | disclosed |
| EP-1898922-A2 | IMPROVED DRUG OR PHARMACEUTICAL COMPOUNDS AND A PREPARATION THEREOF | Krishnan, Ramu (IN) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007004236-A2 | IMPROVED DRUG OR PHARMACEUTICAL COMPOUNDS AND A PREPARATION THEREOF | KRISHNAN RAMU (IN) | 2007-01-11 | — | — | WO | disclosed |
| EP-1152661-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000047046-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2000-08-17 | — | — | WO | disclosed |