Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.65 |
| ▸ | ARG2 | P78540 | 4/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL4622301 | 1.00 | GSR (0.65) | GSRARG2ARG1NOS2NOS1 | |
| Ornithine Aketoglutarate SCHEMBL272917 | 0.95 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| Ornithine SCHEMBL1539161 | 0.95 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28694100 | 0.86 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28694097 | 0.86 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL27799650 | 0.84 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL27799649 | 0.84 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Carnitine SCHEMBL9901519 | 0.83 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| Levocarnitine SCHEMBL6553881 | 0.83 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| Carnitine SCHEMBL9128766 | 0.83 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117757023-A | High-salt low-permeability oil reservoir oil displacement agent containing betaine type surfactant and preparation method thereof | 西安石油大油气科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| EP-1446096-A1 | TOPICAL COMPOSITIONS CONTAINING ENZYMES STABILISED WITH INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-18 | — | — | EP | claimed |
| EP-1446090-A2 | COMPOSITIONS CONTAINING ENZYMES STABILIZED WITH CERTAIN OSMO-PROTECTANTS AND METHODS FOR USING SUCH COMPOSITIONS IN PERSONAL CARE | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-18 | — | — | EP | claimed |
| US-20030175232-A1 | Compositions containing enzymes stabilized with certain osmo-protectants and methods for using such compositions in personal care | THE PROCTER & GAMBLE COMPANY | 2003-09-18 | — | — | US | claimed |
| US-20030157088-A1 | Compositions containing enzymes stabilized with inhibitors having certain binding properties and methods for using such compositions in personal care | THE PROCTOR & GAMBLE COMPANY | 2003-08-21 | — | — | US | claimed |
| WO-2003041680-A1 | TOPICAL COMPOSITIONS CONTAINING ENZYMES STABILIZED WITH INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2003-05-22 | — | — | WO | claimed |
| WO-2003041667-A2 | COMPOSITIONS CONTAINING ENZYMES STABILIZED WITH CERTAIN OSMO-PROTECTANTS AND METHODS FOR USING SUCH COMPOSITIONS IN PERSONAL CARE | THE PROCTER & GAMBLE COMPANY (US) | 2003-05-22 | — | — | WO | claimed |
| EP-1009862-A1 | RAPID DETECTION AND IDENTIFICATION OF MICRO-ORGANISMS | Microscreen B.V. (NL) | 2000-06-21 | — | — | EP | claimed |
| WO-1999010533-A1 | RAPID DETECTION AND IDENTIFICATION OF MICRO-ORGANISMS | MICROSCREEN B.V. (NL) | 1999-03-04 | — | — | WO | claimed |
| JP-1275511-A | — | — | None | — | — | JP | disclosed |
| JP-1275516-A | — | — | None | — | — | JP | disclosed |
| CN-118207050-A | Composition for semiconductor processing and processing method | JSR株式会社 | 2024-06-18 | — | — | CN | disclosed |
| US-20240124734-A1 | Aqueous Ink Jet Ink Composition And Ink Jet Recording Method | SEIKO EPSON CORPORATION (JP) | 2024-04-18 | — | — | US | disclosed |
| CN-117777784-A | Aqueous inkjet ink composition and inkjet recording method | 精工爱普生株式会社 | 2024-03-29 | — | — | CN | disclosed |
| EP-1009862-A1 | RAPID DETECTION AND IDENTIFICATION OF MICRO-ORGANISMS | Microscreen B.V. (NL) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999010533-A1 | RAPID DETECTION AND IDENTIFICATION OF MICRO-ORGANISMS | MICROSCREEN B.V. (NL) | 1999-03-04 | — | — | WO | disclosed |
| EP-0805674-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | Kao Corporation (JP) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997014401-A1 | SKIN AND HAIR COSMETIC COMPOSITIONS | KAO CORPORATION (JP) | 1997-04-24 | — | — | WO | disclosed |
| JP-H01275516-A | DANDRUFF-PREVENTIVE AGENT AND HAIR-COSMETIC | SHISEIDO CO LTD | 1989-11-06 | — | — | JP | disclosed |
| JP-H01275511-A | EXTERNAL DRUG FOR SKIN | SHISEIDO CO LTD | 1989-11-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030175232-A1 | Compositions containing enzymes stabilized with certain osmo-protectants and methods for using such compositions in personal care | TREH, CUTA, LPO | GSR 3035/4885ARG2 1850/4885ARG1 624/4885 |
| US-20030157088-A1 | Compositions containing enzymes stabilized with inhibitors having certain binding properties and methods for using such compositions in personal care | CUTA, LCT, TYR | GSR 4703/4885ARG2 1923/4885ARG1 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.