SCHEMBL462259

SCHEMBL462259

CCC=CC(CC(=O)O)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
CYP19A1 P11511 4/20 0.34
PPARG P37231 3/20 0.34
OXER1 Q8TDS5 3/20 0.34
MAPT P10636 3/20 0.34
RXRA P19793 2/20 0.34
FFAR1 O14842 2/20 0.34
GRIK1 P39086 3/20 0.33
GRIK2 Q13002 3/20 0.33
FPR2 P25090 1/20 0.33
F7 P08709 3/20 0.32
F3 P13726 3/20 0.32
PTGS1 P23219 2/20 0.32
KMT2A Q03164 2/20 0.32
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
HDAC2 Q92769 1/20 0.32
GABRR1 P24046 2/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL854312 1.00 ALDH1A1 (0.34) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL28285494 0.98 ALDH1A1 (0.33) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL29287443 0.86 LMNA (0.32) ALDH1A1LMNAKDM4EALOX15TDP1
SCHEMBL570082 0.86 GRIK1 (0.31) GRIK1GRIK2KMT2AMEN1CYP3A4
SCHEMBL462258 0.86 GRIK1 (0.31) GRIK1GRIK2KMT2AMEN1CYP3A4
SCHEMBL40726 0.83 TDP1 (0.37) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL29962280 0.83 TDP1 (0.37) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL40727 0.83 TDP1 (0.37) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL28832993 0.82 TDP1 (0.36) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL161176 0.79 TERT (0.50) CYP19A1PPARGMAPTF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024031075-A1 MIXED COMPONENT TRACTION FLUIDS VANTAGE SANTOLUBES RESEARCH LLC (US) 2024-02-08 WO claimed
EP-2913386-B1 DIOCTYL SEBACATE IN ENGINE OILS FUCHS PETROLUB SE (DE) 2020-09-09 EP claimed
CN-111303965-A Antioxidant self-repairing lubricating oil containing graphene oxide 广东凯穗润滑油科技有限公司 2020-06-19 CN claimed
CN-106350154-B The method and purposes of a kind of power transmitting fluids and its dynamic energy for improving wet clutch 英菲诺姆国际有限公司 2019-11-05 CN claimed
CN-108587750-A A kind of vehicle lubricating oil 江苏中威重工机械有限公司 2018-09-28 CN claimed
CN-108285820-A A kind of improved vehicle lubricating oil 海安吉德机电技术开发有限公司 2018-07-17 CN claimed
CN-108192701-A A kind of novel automobile aqueous lubricating ointment 海安国洋机械科技有限公司 2018-06-22 CN claimed
CN-108059997-A A kind of modified lubricating oil 海安吉德机电技术开发有限公司 2018-05-22 CN claimed
CN-105001940-B A kind of refrigerator oil and refrigeration compressor and system 上海铭朔化工科技有限公司 2018-04-20 CN claimed
CN-104927994-B Refrigerator oil and refrigeration compressor and system 上海铭朔化工科技有限公司 2018-01-05 CN claimed
CN-106560506-A Additive concentrates for formulating lubricating oil compositions 英菲诺姆国际有限公司 2017-04-12 CN claimed
CN-104145010-B Lubricating oil composition 出光兴产株式会社 2016-08-31 CN claimed
CN-105001940-A Refrigerator oil and refrigeration compressor and system SHANGHAI MINGSHUO CHEMICAL TECHNOLOGY CO LTD 2015-10-28 CN claimed
CN-104927994-A Refrigerating machine oil and refrigeration compressor and system SHANGHAI MINGSHUO CHEMICAL TECHNOLOGY CO LTD 2015-09-23 CN claimed
EP-4370634-A1 2-OCTANOL MONOESTER AS LUBRICANT ARKEMA FRANCE (FR) 2024-05-22 EP disclosed
WO-2024031075-A1 MIXED COMPONENT TRACTION FLUIDS VANTAGE SANTOLUBES RESEARCH LLC (US) 2024-02-08 WO disclosed
US-11820952-B2 Process to produce low shear strength base oils VANTAGE SANTOLUBES RESEARCH LLC (US) 2023-11-21 US disclosed
US-4959167-A WEAR RESISTANCE, CORROSION RESISTANCE, HIGH PRESSURE CIBA-GEIGY CORPORATION (US) 1990-09-25 US disclosed
US-4863887-A Additive for the hydroconversion of a heavy hydrocarbon oil ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1989-09-05 US disclosed
EP-0271337-A2 An Additive for the hydroconversion of a heavy hydrocarbon oil Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-06-15 EP disclosed