SCHEMBL854312

SCHEMBL854312

CC/C=C/C(CC(=O)O)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
CYP19A1 P11511 4/20 0.34
PPARG P37231 3/20 0.34
OXER1 Q8TDS5 3/20 0.34
MAPT P10636 3/20 0.34
RXRA P19793 2/20 0.34
FFAR1 O14842 2/20 0.34
GRIK1 P39086 3/20 0.33
GRIK2 Q13002 3/20 0.33
FPR2 P25090 1/20 0.33
F7 P08709 3/20 0.32
F3 P13726 3/20 0.32
PTGS1 P23219 2/20 0.32
KMT2A Q03164 2/20 0.32
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
ADORA3 P0DMS8 1/20 0.32
HDAC2 Q92769 1/20 0.32
GABRR1 P24046 2/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL462259 1.00 ALDH1A1 (0.34) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL28285494 0.98 ALDH1A1 (0.33) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL29287443 0.86 LMNA (0.32) ALDH1A1LMNAKDM4EALOX15TDP1
SCHEMBL570082 0.86 GRIK1 (0.31) GRIK1GRIK2KMT2AMEN1CYP3A4
SCHEMBL462258 0.86 GRIK1 (0.31) GRIK1GRIK2KMT2AMEN1CYP3A4
SCHEMBL40726 0.83 TDP1 (0.37) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL29962280 0.83 TDP1 (0.37) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL40727 0.83 TDP1 (0.37) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL28832993 0.82 TDP1 (0.36) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL161176 0.79 TERT (0.50) CYP19A1PPARGMAPTF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105001940-B A kind of refrigerator oil and refrigeration compressor and system 上海铭朔化工科技有限公司 2018-04-20 CN claimed
CN-104927994-B Refrigerator oil and refrigeration compressor and system 上海铭朔化工科技有限公司 2018-01-05 CN claimed
CN-105001940-A Refrigerator oil and refrigeration compressor and system SHANGHAI MINGSHUO CHEMICAL TECHNOLOGY CO LTD 2015-10-28 CN claimed
CN-104927994-A Refrigerating machine oil and refrigeration compressor and system SHANGHAI MINGSHUO CHEMICAL TECHNOLOGY CO LTD 2015-09-23 CN claimed
US-20220177408-A1 LUBRICATING BASE OIL SYNTHESIZED FROM SUGAR ALCOHOL ESTERS ARKEMA FRANCE (FR) 2022-06-09 US disclosed
WO-2022060772-A1 ENVIRONMENTALLY FRIENDLY REFRIGERANT COMPOSITIONS FLUOROFUSION SPECIALTY CHEMICALS, INC. (US) 2022-03-24 WO disclosed
US-11274180-B2 Use of hydrophobically modified polyalkanolamines as wax inhibitors, pour point depressant and additive for lubricants BASF SE (DE) 2022-03-15 US disclosed
US-11214752-B2 Lubricant composition containing copolymers of polyisobutylenemethacrylate BASF SE (DE) 2022-01-04 US disclosed
US-11208583-B1 Environmentally friendly refrigerant compositions having low flammability and low GWP FluoroTek, L.L.C. (US) 2021-12-28 US disclosed
EP-3917906-A1 LUBRICATING BASE OIL SYNTHESIZED FROM SUGAR ALCOHOL ESTERS ARKEMA FRANCE (FR) 2021-12-08 EP disclosed
EP-3918042-A1 LUBRICATING BASE OIL SYNTHESIZED FROM POLYOL ESTERS AND BIOSOURCED FATTY ACIDS ARKEMA FRANCE (FR) 2021-12-08 EP disclosed
US-11028300-B1 Environmentally friendly refrigerant compositions THE COULAN COMPANY, L.L.C. 2021-06-08 US disclosed
WO-1993024585-A1 POLYOL ESTER LUBRICANTS FOR REFRIGERANT HEAT TRANSFER FLUIDS HENKEL CORPORATION (US) 1993-12-09 WO disclosed
WO-1993024588-A1 POLYOL ESTER LUBRICANTS FOR HIGH EFFICIENCY REFRIGERATORS HENKEL CORPORATION (US) 1993-12-09 WO disclosed
WO-1993024587-A1 BLENDED POLYOL ESTER LUBRICANTS FOR REFRIGERANT HEAT TRANSFER FLUIDS HENKEL CORPORATION (US) 1993-12-09 WO disclosed
EP-0557279-A1 LUBRICANT FOR REFRIGERANT HEAT TRANSFER FLUIDS. HENKEL CORP (US) 1993-09-01 EP disclosed
US-5167844-A Stabilized against thermal and oxidative degradation CIBA-GEIGY CORPORATION (US) 1992-12-01 US disclosed
WO-1992001030-A1 LUBRICANT FOR REFRIGERANT HEAT TRANSFER FLUIDS HENKEL CORPORATION (US) 1992-01-23 WO disclosed
US-5021179-A Mixture of fluorocarbon refrigerant heat transfer fluid and ester HENKEL CORPORATION (US) 1991-06-04 US disclosed
US-4959167-A WEAR RESISTANCE, CORROSION RESISTANCE, HIGH PRESSURE CIBA-GEIGY CORPORATION (US) 1990-09-25 US disclosed