Acetoacetic Acid

Acetoacetic Acid

SCHEMBL4622741

CC(=O)CC(=O)O.CC(C)(C)C(=O)CC(=O)O

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
KDM6B O15054 1/20 0.41
KDM5C P41229 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
PHF8 Q9UPP1 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
LMNA P02545 1/20 0.36
SLC15A2 Q16348 1/20 0.36
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
KMT2A Q03164 1/20 0.34
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL954279 0.89 LDHA (0.47) KDM4EEGLN1LDHASRRLMNA
SCHEMBL14715593 0.87 LDHA (0.44) KDM4ELDHASRRHMGCRCHRM1
SCHEMBL46501 0.84 MGAM (0.41) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL10916658 0.84
Acetoacetic Acid SCHEMBL28774893 0.81 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL29640532 0.81 MGAM (0.39) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28048455 0.81 MGAM (0.39) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL7718675 0.81 EGLN1 (0.50) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL7718676 0.81 EGLN1 (0.50) KDM4EKDM6BKDM5CEGLN1PHF8
Acetoacetic Acid SCHEMBL1406366 0.81 LDHA (0.57) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1371752-B1 Layer formation method, and substrate with a layer formed by the method KONICA CORP (JP) 2008-05-07 EP disclosed
US-7166335-B2 Layer formation method, and substrate with a layer formed by the method KONICA CORPORATION (JP) 2007-01-23 US disclosed
US-20040213920-A1 Layer formation method, and substrate with a layer formed by the method KONICA CORPORATION (JP) 2004-10-28 US disclosed
US-6759100-B2 ATMOSPHERIC PRESSURE PLASMA DISCHARGE TREATMENT; CHEAP AND SAFE DISCHARGE GAS SUCH AS NITROGEN KONICA CORPORATION (JP) 2004-07-06 US disclosed
US-20030232136-A1 Layer formation method, and substrate with a layer formed by the method KONICA CORPORATION (JP) 2003-12-18 US disclosed
EP-1371752-A2 Layer formation method, and substrate with a layer formed by the method KONICA CORPORATION (JP) 2003-12-17 EP disclosed