Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715593 | 0.97 | LDHA (0.44) | LDHASRRHMGCRCHRM1TBXA2R | |
| Acetoacetic Acid SCHEMBL4622741 | 0.89 | KDM4E (0.41) | LDHASRRHMGCRCHRM1TBXA2R | |
| Nitrous Acid SCHEMBL27764796 | 0.89 | LDHA (0.38) | LDHASRRHMGCRCHRM1TBXA2R | |
| SCHEMBL7165273 | 0.86 | LDHA (0.40) | LDHASRRHMGCRCHRM1TBXA2R | |
| SCHEMBL93393 | 0.83 | KMT2A (0.39) | HMGCRCHRM1TBXA2RADRA1AKMT2A | |
| SCHEMBL4837194 | 0.83 | KMT2A (0.39) | HMGCRCHRM1TBXA2RADRA1AKMT2A | |
| SCHEMBL15788938 | 0.80 | KMT2A (0.37) | HMGCRCHRM1TBXA2RADRA1AKMT2A | |
| SCHEMBL9325238 | 0.80 | KMT2A (0.37) | HMGCRCHRM1TBXA2RADRA1AKMT2A | |
| SCHEMBL21405194 | 0.80 | KMT2A (0.37) | HMGCRCHRM1TBXA2RADRA1AKMT2A | |
| SCHEMBL21002308 | 0.80 | KMT2A (0.37) | HMGCRCHRM1TBXA2RADRA1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905756-B1 | SILVER BETA-KETOCARBOXYLATE DERIVATIVES FOR FORMING SILVER METAL | UNIV OSAKA (JP) | 2013-02-27 | — | — | EP | claimed |
| EP-1254192-B1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING SA (BE) | 2004-08-04 | — | — | EP | claimed |
| JP-62228041-A | — | — | None | — | — | JP | disclosed |
| US-12508239-B2 | Alcohol derivatives as Kv7 potassium channel openers for use in epilepsy or seizures | H. LUNDBECK A/S (DK) | 2025-12-30 | — | — | US | disclosed |
| EP-4007571-B1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS FOR USE IN EPILEPSY OR SEIZURES | H LUNDBECK AS (DK) | 2025-06-18 | — | — | EP | disclosed |
| EP-4241843-B1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H LUNDBECK AS (DK) | 2025-05-21 | — | — | EP | disclosed |
| US-12258305-B2 | Alcohol derivatives as Kv7 potassium channel openers | H. LUNDBECK A/S (DK) | 2025-03-25 | — | — | US | disclosed |
| CN-119490430-A | Alcohol derivatives as Kv7 potassium channel openers for use in epilepsy or seizures | H.隆德贝克有限公司 | 2025-02-21 | — | — | CN | disclosed |
| EP-4461725-A2 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. Lundbeck A/S (DK) | 2024-11-13 | — | — | EP | disclosed |
| US-20240327336-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2024-10-03 | — | — | US | disclosed |
| EP-4007634-B1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H LUNDBECK AS (DK) | 2024-10-02 | — | — | EP | disclosed |
| WO-1992009661-A1 | SQUARYLIUM AND CROCONYLIUM DYES | POLAROID CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |
| EP-0378068-A1 | New polyfunctional alpha-diazo-beta-keto esters, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-18 | — | — | EP | disclosed |
| EP-0378067-A2 | Positively working radiation-sensitive mixture containing a multifunctional alpha-diazo-beta-keto ester, process for its preparation and a radiation-sensitive recording material containing this mixture | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-18 | — | — | EP | disclosed |
| CN-1031533-A | Stable 1-Oxapenem-3-carboxylic acid | BAYER AG (DE) | 1989-03-08 | — | — | CN | disclosed |
| JP-S62228041-A | PRODUCTION OF CARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUT IND LTD | 1987-10-06 | — | — | JP | disclosed |
| US-4370499-A | CHEMICAL INTERMEDIATES FOR COLOR PHOTOGRAPHY | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4268591-A | YELLOW COUPLER | CIBA-GEIGY AG (CH) | 1981-05-19 | — | — | US | disclosed |
| US-4130430-A | OXONOL DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-12-19 | — | — | US | disclosed |
| US-4031130-A | Aliphatic β-keto esters | AGFA-GEVAERT, A.G. (DT) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327336-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | KCNA7, KCNK17, KCNQ1 | LDHA 2679/4885SRR 3732/4885HMGCR 3250/4885 |
| US-12508239-B2 | Alcohol derivatives as Kv7 potassium channel openers for use in epilepsy or seizures | KCNN3, KCNN1, KCNN2 | LDHA 1416/4885SRR 4274/4885HMGCR 3031/4885 |
| US-12258305-B2 | Alcohol derivatives as Kv7 potassium channel openers | KCNA7, KCNK17, KCNQ1 | LDHA 2679/4885SRR 3732/4885HMGCR 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.