Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622521 | 0.86 | NPC1 (0.41) | NPC1RAB9AHSD17B3HDAC1HDAC8 | |
| SCHEMBL19754953 | 0.86 | HSD17B3 (0.56) | NPC1RAB9ATHRATHRBHSD17B3 | |
| SCHEMBL4621264 | 0.85 | NPC1 (0.40) | NPC1RAB9AHSD17B3HDAC1HDAC8 | |
| SCHEMBL3672211 | 0.85 | NPC1 (0.41) | NPC1RAB9AHSD17B3HDAC1HDAC8 | |
| SCHEMBL2762922 | 0.78 | NPC1 (0.42) | NPC1RAB9ATHRATHRBHSD17B3 | |
| SCHEMBL3680703 | 0.78 | NPC1 (0.42) | NPC1RAB9ATHRATHRBHSD17B3 | |
| SCHEMBL10471647 | 0.78 | MAPT (0.53) | NPC1RAB9ATHRATHRBHSD17B3 | |
| SCHEMBL4686360 | 0.75 | ALDH1A1 (0.43) | NPC1RAB9ATHRATHRBHSD17B3 | |
| SCHEMBL11277802 | 0.73 | GSK3B (0.64) | NPC1RAB9ATHRATHRBHSD17B3 | |
| SCHEMBL307335 | 0.73 | EPHX2 (0.44) | RAB9AHDAC1MAPTLMNARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307423-B1 | PROCESSES FOR THE PRODUCTION OF FEXOFENADINE | TEXCONTOR ETS (LI) | 2008-03-19 | — | — | EP | disclosed |
| US-7176318-B2 | Processes for the production of fexofenadine | TEXCONTOR ESTABLISSEMENT (LI) | 2007-02-13 | — | — | US | disclosed |
| US-20030166682-A1 | Processes for the production of fexofenadine | TEXCONTOR ETABLISSEMENT (LI) | 2003-09-04 | — | — | US | disclosed |
| EP-1307423-A1 | NEW PROCESSES FOR THE PRODUCTION OF FEXOFENADINE | Texcontor Etablissement (LI) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010115-A1 | NEW PROCESSES FOR THE PRODUCTION OF FEXOFENADINE | TEXCONTOR ETABLISSEMENT (LI) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166682-A1 | Processes for the production of fexofenadine | AOC1, COX6C, AOC3 | NPC1 3218/4885RAB9A 849/4885THRA 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.