Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622882 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL1502465 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL1502354 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL28370678 | 0.84 | GSK3B (0.54) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL24171986 | 0.83 | ACHE (0.43) | LMNATDP1CNR1CNR2MAPT | |
| SCHEMBL31121940 | 0.83 | ACHE (0.43) | LMNATDP1CNR1CNR2MAPT | |
| SCHEMBL3680703 | 0.83 | NPC1 (0.42) | LMNATDP1PDE4BHDAC1HDAC8 | |
| SCHEMBL4960271 | 0.82 | KMT2A (0.53) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL12139296 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL24172494 | 0.81 | BRS3 (0.50) | CNR1CNR2HDAC1HDAC8THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130237709-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF FEXOFENADINE, PROCESSES FOR THEIR PREPARATION AND FOR THE PREPARATION OF FEXOFENADINE | CHEMELECTIVA S.R.L. (IT) | 2013-09-12 | — | — | US | disclosed |
| EP-1307423-B1 | PROCESSES FOR THE PRODUCTION OF FEXOFENADINE | TEXCONTOR ETS (LI) | 2008-03-19 | — | — | EP | disclosed |
| US-7176318-B2 | Processes for the production of fexofenadine | TEXCONTOR ESTABLISSEMENT (LI) | 2007-02-13 | — | — | US | disclosed |
| US-20030166682-A1 | Processes for the production of fexofenadine | TEXCONTOR ETABLISSEMENT (LI) | 2003-09-04 | — | — | US | disclosed |
| EP-1307423-A1 | NEW PROCESSES FOR THE PRODUCTION OF FEXOFENADINE | Texcontor Etablissement (LI) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010115-A1 | NEW PROCESSES FOR THE PRODUCTION OF FEXOFENADINE | TEXCONTOR ETABLISSEMENT (LI) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237709-A1 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF FEXOFENADINE, PROCESSES FOR THEIR PREPARATION AND FOR THE PREPARATION OF FEXOFENADINE | CYP2F1, CYP4F2, NISCH | ALDH1A1 619/4885LMNA 4010/4885ALOX15 558/4885 |
| US-20030166682-A1 | Processes for the production of fexofenadine | AOC1, COX6C, AOC3 | ALDH1A1 78/4885LMNA 4816/4885ALOX15 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.