Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623311 | 1.00 | REN (0.50) | REN | |
| SCHEMBL2440502 | 1.00 | REN (0.50) | REN | |
| SCHEMBL19304579 | 1.00 | REN (0.50) | REN | |
| SCHEMBL3947837 | 1.00 | REN (0.50) | REN | |
| SCHEMBL19304576 | 1.00 | REN (0.50) | REN | |
| SCHEMBL19304577 | 1.00 | REN (0.50) | REN | |
| SCHEMBL6045352 | 0.92 | REN (0.48) | REN | |
| SCHEMBL6044937 | 0.92 | REN (0.48) | REN | |
| SCHEMBL10119482 | 0.92 | REN (0.49) | REN | |
| SCHEMBL10144615 | 0.91 | REN (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056816-B2 | Process for the preparation of aliskiren | JUBILANT LIFE SCIENCES LIMITED (IN) | 2015-06-16 | — | — | US | disclosed |
| US-9056816-B2 | Process for the preparation of aliskiren | JUBILANT LIFE SCIENCES LIMITED (IN) | 2015-06-16 | — | — | US | disclosed |
| EP-2393489-B1 | Moisture-activated granulation process | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2014-10-08 | — | — | EP | disclosed |
| US-20140256963-A1 | PROCESS FOR THE PREPARATION OF ALISKIREN | Jubilant Generics Limited (IN) | 2014-09-11 | — | — | US | disclosed |
| US-20140256963-A1 | PROCESS FOR THE PREPARATION OF ALISKIREN | Jubilant Generics Limited (IN) | 2014-09-11 | — | — | US | disclosed |
| WO-2013061224-A1 | PROCESS FOR THE PREPARATION OF ALISKIREN | JUBILANT LIFE SCIENCES LIMITED (IN) | 2013-05-02 | — | — | WO | disclosed |
| WO-2012034065-A1 | ALISKIREN INTERMEDIATES AND A PROCESS FOR ANALYZING THE PURITY OF ALISKIREN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2012-03-15 | — | — | WO | disclosed |
| US-20110244531-A1 | SYNTHESIS ROUTES TO 2(S),4(S),5(S),7(S)-2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES | JLL/DELTA DUTCH NEWCO B.V. (NL) | 2011-10-06 | — | — | US | disclosed |
| US-20110244531-A1 | SYNTHESIS ROUTES TO 2(S),4(S),5(S),7(S)-2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES | JLL/DELTA DUTCH NEWCO B.V. (NL) | 2011-10-06 | — | — | US | disclosed |
| EP-1904469-B1 | NEW PYROCATECHIN DERIVATIVES | NOVARTIS AG (CH) | 2011-09-21 | — | — | EP | disclosed |
| US-20090143340-A1 | Pyrocatechin Derivatives | SEDELMEIER GOTTFRIED | 2009-06-04 | — | — | US | disclosed |
| WO-2009049837-A1 | PROCESS FOR PREPARING 8-HYDRAZINO-8-ARYLOCTANOYL DERIVATIVES AND THEIR USE | REUTER CHEMISCHER APPARATEBAU KG (DE) | 2009-04-23 | — | — | WO | disclosed |
| US-20090076062-A1 | Organic Compounds | MAIBAUM JUERGEN KLAUS | 2009-03-19 | — | — | US | disclosed |
| US-20090076062-A1 | Organic Compounds | MAIBAUM JUERGEN KLAUS | 2009-03-19 | — | — | US | disclosed |
| WO-2006024501-A1 | ALTERNATIVE SYNTHESIS OF RENIN INHIBITORS AND INTERMEDIATES THEREOF | NOVARTIS AG (CH) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143340-A1 | Pyrocatechin Derivatives | CYP3A43, CYP4B1, CYP4A22 | REN 798/4885 |
| US-20140256963-A1 | PROCESS FOR THE PREPARATION OF ALISKIREN | REN, HK1, KHK | REN 1/4885 |
| US-20110244531-A1 | SYNTHESIS ROUTES TO 2(S),4(S),5(S),7(S)-2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES | KHK, AGTR2, HK2 | REN 206/4885 |
| US-20090076062-A1 | Organic Compounds | AGTR1, AGTR2, REN | REN 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.