Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methyl Phosphonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Phosphonate SCHEMBL1303323 | 0.89 | — | — | |
| SCHEMBL190771 | 0.89 | CA2 (0.42) | — | |
| Methyl Phosphonate SCHEMBL7313766 | 0.89 | — | — | |
| Methyl Phosphonate SCHEMBL7757487 | 0.89 | CA2 (0.42) | — | |
| Methyl Phosphonate SCHEMBL1820657 | 0.89 | — | — | |
| Methyl Phosphonate SCHEMBL4621159 | 0.89 | — | — | |
| Methyl Phosphonate SCHEMBL11394617 | 0.89 | CA2 (0.42) | — | |
| Methyl Phosphonate SCHEMBL10687038 | 0.89 | — | — | |
| Methyl Phosphonate SCHEMBL20597974 | 0.89 | — | — | |
| Methyl Phosphonate SCHEMBL7075062 | 0.89 | CA2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739122-B1 | Polymer compositions containing salts of phosphonic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2008-03-26 | — | — | EP | claimed |
| US-20070029532-A1 | Flame retardant preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2007-02-08 | — | — | US | claimed |
| EP-1749852-A1 | fire retardant composition | Lanxess Deutschland GmbH (DE) | 2007-02-07 | — | — | EP | claimed |
| EP-1739122-A1 | Polymer compositions containing salts of phosphonic acids | Lanxess Deutschland GmbH (DE) | 2007-01-03 | — | — | EP | claimed |
| CN-118510771-A | IRAK inhibitors for the treatment of conditions associated with cytokine release associated with respiratory viral infection | 里格尔药品股份有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-116601161-A | Prodrugs of 2- (3, 5-dichloro-1-methyl-indazol-4-yl) -1- [ (1 s,3 r) -3- (hydroxymethyl) -5- (1-hydroxy-1-methyl-ethyl) -1-methyl-3, 4-dihydro-1H-isoquinolin-2-yl ] ethanone | UCB生物制药有限责任公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-1739122-B1 | Polymer compositions containing salts of phosphonic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2008-03-26 | — | — | EP | disclosed |
| US-20070029532-A1 | Flame retardant preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2007-02-08 | — | — | US | disclosed |
| EP-1749852-A1 | fire retardant composition | Lanxess Deutschland GmbH (DE) | 2007-02-07 | — | — | EP | disclosed |
| EP-1739122-A1 | Polymer compositions containing salts of phosphonic acids | Lanxess Deutschland GmbH (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-0458150-B1 | Process for producing shaped articles | BAYER AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| US-5194198-A | PROCESS FOR THE PRODUCTION OF MOULDED ARTICLES OF EXPANDED GRAPHITE | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0458150-A1 | Process for producing shaped articles | BAYER AG (DE) | 1991-11-27 | — | — | EP | disclosed |