Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.43 |
| ▸ | PDE1A | P54750 | 3/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646522 | 0.85 | KDM4E (0.44) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL4796596 | 0.85 | PDE1A (0.46) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL7007230 | 0.84 | MEN1 (0.50) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL9160664 | 0.83 | PDE5A (0.44) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL5646 | 0.79 | PDE2A (0.61) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL3110928 | 0.78 | PNP (0.48) | PDE5AMEN1KMT2ATSHRKDM4E | |
| SCHEMBL19583186 | 0.77 | KDM4E (0.43) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL272517 | 0.75 | KDM4E (0.41) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL6234430 | 0.75 | PDE5A (0.64) | PDE5APDE1APDE1BPDE1CMEN1 | |
| SCHEMBL9645631 | 0.74 | ADORA2A (0.40) | PDE5APDE1APDE1BPDE1CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904020-A2 | NEW SLIMMING COSMETIC COMPOSITIONS | Sederma S.A.S. (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010478-A2 | SLIMMING COSMETIC COMPOSITIONS | SEDERMA (FR) | 2007-01-25 | — | — | WO | disclosed |