Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623900 | 0.96 | TLR8 (0.47) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL17504176 | 0.72 | MEN1 (0.48) | MEN1KMT2APOLBTSHRALDH1A1 | |
| SCHEMBL27306881 | 0.69 | TLR8 (0.51) | TLR8TSHRSMPD1ENPP2NPC1 | |
| SCHEMBL5545591 | 0.69 | ENPP2 (0.48) | MEN1KMT2ATLR8POLBSMPD1 | |
| SCHEMBL11679229 | 0.69 | CYP19A1 (0.49) | MEN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL13656325 | 0.68 | MEN1 (0.44) | MEN1KMT2APOLBTSHRSMPD1 | |
| SCHEMBL14180976 | 0.66 | CNR1 (0.52) | MEN1KMT2APOLBTSHRSMPD1 | |
| SCHEMBL2341868 | 0.65 | TSHR (0.64) | MEN1KMT2ATLR8POLBTSHR | |
| SCHEMBL11393727 | 0.65 | HSD17B10 (0.50) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL13656326 | 0.64 | MEN1 (0.41) | MEN1KMT2APOLBTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328275-B1 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-07 | — | — | EP | disclosed |
| US-6995157-B2 | Substituted 4,5-dihydro-1,2,4-triazin-3-ones, 1,2,4-triazin-3-ones, and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2006-02-07 | — | — | US | disclosed |
| EP-1328275-A4 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20040019209-A1 | Substituted 4,5-dihydro-1,2,4-triazin-3-ones,1,2,4-triazin-3-ones, and their use as fungicides and insecticides | DOW AGROSCIENCES LLC | 2004-01-29 | — | — | US | disclosed |
| EP-1328275-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | Dow AgroSciences LLC (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002056682-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-3-ONES, 1,2,4-TRIAZIN-3-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2002-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019209-A1 | Substituted 4,5-dihydro-1,2,4-triazin-3-ones,1,2,4-triazin-3-ones, and their use as fungicides and insecticides | DDT, CYP4B1, CYP4X1 | MEN1 2524/4885KMT2A 1489/4885GABRP 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.