Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501339 | 0.80 | BRD4 (0.58) | BRD4PNPKMT2AMEN1KDM4E | |
| SCHEMBL23974903 | 0.79 | PDE1A (0.49) | KMT2AKDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL9328835 | 0.79 | BRD4 (0.72) | BRD4PNPKMT2AMEN1KDM4E | |
| SCHEMBL190991 | 0.78 | ALDH1A1 (0.53) | BRD4KMT2AMEN1KDM4EMAPT | |
| SCHEMBL5647 | 0.78 | ADORA2A (0.43) | KMT2AMEN1KDM4EHPGDALDH1A1 | |
| SCHEMBL3115743 | 0.78 | ALDH1A1 (0.51) | BRD4PNPKMT2AMEN1KDM4E | |
| SCHEMBL4623646 | 0.77 | ADORA2B (0.45) | KMT2AMEN1POLBNOD2NOD1 | |
| SCHEMBL4621732 | 0.77 | ADORA2A (0.43) | KMT2AMEN1KDM4EHTTMAPT | |
| SCHEMBL3110932 | 0.77 | PDE1A (0.53) | BRD4PNPKMT2AMEN1HPGD | |
| SCHEMBL23974900 | 0.76 | ADORA3 (0.52) | KMT2AMEN1POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904020-A2 | NEW SLIMMING COSMETIC COMPOSITIONS | Sederma S.A.S. (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010478-A2 | SLIMMING COSMETIC COMPOSITIONS | SEDERMA (FR) | 2007-01-25 | — | — | WO | disclosed |