Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462652 | 0.86 | NPC1 (0.31) | NPC1LMNAMAPTHTT | |
| SCHEMBL461635 | 0.78 | GPR119 (0.44) | — | |
| SCHEMBL146465 | 0.74 | GPR119 (0.34) | LMNAALOX5AP | |
| SCHEMBL120997 | 0.74 | GPR119 (0.34) | LMNAALOX5AP | |
| SCHEMBL470673 | 0.67 | OPRK1 (0.31) | — | |
| SCHEMBL457626 | 0.67 | GPR119 (0.46) | — | |
| SCHEMBL459489 | 0.66 | PIM1 (0.35) | — | |
| SCHEMBL12146586 | 0.64 | SMN1; SMN2 (0.45) | MAPTHTT | |
| SCHEMBL12506056 | 0.64 | GPR119 (0.59) | LMNAMAPTALOX5AP | |
| SCHEMBL462366 | 0.61 | ALOX5AP (0.37) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |