Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462489 | 0.86 | NPC1 (0.32) | NPC1LMNAMAPTHTT | |
| SCHEMBL461635 | 0.77 | GPR119 (0.44) | — | |
| SCHEMBL470828 | 0.76 | DPP4 (0.32) | — | |
| SCHEMBL120997 | 0.73 | GPR119 (0.34) | LMNA | |
| SCHEMBL146465 | 0.73 | GPR119 (0.34) | LMNA | |
| SCHEMBL25071608 | 0.69 | PIM1 (0.38) | — | |
| SCHEMBL470673 | 0.66 | OPRK1 (0.31) | — | |
| SCHEMBL12146586 | 0.63 | SMN1; SMN2 (0.45) | MAPTHTT | |
| SCHEMBL459837 | 0.63 | — | — | |
| SCHEMBL19450682 | 0.62 | LMNA (0.41) | NPC1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |