SCHEMBL4625366

SCHEMBL4625366

CCCCc1[c]cc(C)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.33
MAPT P10636 1/20 0.33
SKP2 Q13309 1/20 0.32
NOS2 P35228 1/20 0.32
NPC1 O15118 2/20 0.31
MAPK1 P28482 2/20 0.31
RAB9A P51151 2/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15061557 0.94 ESR1 (0.34) HTTTP53ALDH1A1
SCHEMBL1134431 0.87 ACHE (0.30)
SCHEMBL1539433 0.79 CA2 (0.42) SKP2HPGDTP53SMN1; SMN2CA1
SCHEMBL455980 0.78
SCHEMBL28310090 0.78 HTR7 (0.35) HTTMAPTHPGDALDH1A1
SCHEMBL6848066 0.78 TYR (0.44) HTTMAPTNPC1MAPK1RAB9A
SCHEMBL28309274 0.78 MEN1 (0.36) NPC1RAB9ASMN1; SMN2
SCHEMBL21268399 0.78
SCHEMBL21268375 0.78 CA2 (0.37) SKP2HPGDTP53SMN1; SMN2CA1
SCHEMBL21268276 0.78 NPC1 (0.37) SKP2NPC1MAPK1RAB9ANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029144-A1 FILM FOR AGRICULTURAL USE, RESIN COMPOSITION FOR FORMING FILM FOR AGRICULTURAL USE, AND METHOD FOR GROWING PLANT USING SAME 株式会社ADEKA 2021-02-18 WO disclosed
WO-2020230664-A1 AGRICULTURAL FILM AND PLANT GROWING METHOD 株式会社ADEKA 2020-11-19 WO disclosed
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 EP disclosed
CN-107033798-A Surface protection film, manufacture method and substrate processing layered product 信越化学工业株式会社 2017-08-11 CN disclosed
CN-105461589-A Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals SANOFI AVENTIS 2016-04-06 CN disclosed
CN-105418450-A ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS SANOFI AVENTIS 2016-03-23 CN disclosed
EP-1725610-B1 BIOCIDAL COMPOSITIONS AND METHODS OF MAKING THEREOF GEN ELECTRIC (US) 2008-01-09 EP disclosed
EP-1689580-A1 MULTIWALL SHEETS AND METHODS FOR MANUFACTURING THEREOF General Electric Company (US) 2006-08-16 EP disclosed
WO-2005053953-A1 MULTIWALL SHEETS AND METHODS FOR MANUFACTURING THEREOF GENERAL ELECTRIC COMPANY (US) 2005-06-16 WO disclosed
EP-0636130-A1 AZACYCLIC COMPOUNDS MERCK SHARP & DOHME LTD. (GB) 1995-02-01 EP disclosed
EP-0180992-A2 Stabilizer compositions for synthetic resins imparting improved light stability ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1986-05-14 EP disclosed
US-4396735-A N-HETEROCYCLIC COMPOUND AND A HETEROCYCLIC ACID HYDRAZIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-08-02 US disclosed
EP-0046161-A2 Stabilized Polyvinylhalide resin PHOENIX CHEMICAL CORPORATION (US) 1982-02-24 EP disclosed
US-4279805-A Alkylene-bis-thioalkanoic acid amide stabilizers for synthetic resins and synthetic resin compositions containing the same ARGUS CHEMICAL CORPORATION (US) 1981-07-21 US disclosed
EP-0024919-A2 Process for providing monovalent and polyvalent metal, particularly antimony, mercaptocarboxylic acid ester salts; monovalent and polyvalent metal mercaptocarboxylic acid salts; polyol mercaptocarboxylic acid monoesters, and esters of such polyol mercaptocarboxylic acid esters with a mercaptocarboxylic acid; stabilizer compositions for polyvinyl chloride resins comprising such compounds; and polyvinyl chloride resin compositions comprising a stabilizing amount of such compounds Mack, Gerry (US) 1981-03-11 EP disclosed
US-4222931-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant ARGUS CHEMICAL CORPORATION (US) 1980-09-16 US disclosed
US-4210577-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-07-01 US disclosed
US-4110306-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, a triphosphite, and an acid phosphite or salt thereof ARGUS CHEMICAL CORPORATION (US) 1978-08-29 US disclosed