SCHEMBL4625495

SCHEMBL4625495

CCOC(=O)c1cccc(Cl)c1C(=O)OCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ALDH1A1 P00352 5/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 4/20 0.49
MAPK1 P28482 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PDE4B Q07343 1/20 0.49
CDC25B P30305 2/20 0.49
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
BAZ2B Q9UIF8 1/20 0.49
BAZ2A Q9UIF9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4626642 0.90 TSHR (0.60) TSHRCA12CA1CA2CA7
SCHEMBL4628289 0.90 ALDH1A1 (0.58) TSHRCA12CA1CA2CA7
SCHEMBL4628606 0.90 TSHR (0.50) TSHRCA12CA1CA2CA7
SCHEMBL8493097 0.89 CA12 (0.66) TSHRCA12CA1CA2CA7
SCHEMBL4626983 0.88 TSHR (0.51) TSHRCA12CA1CA2CA7
SCHEMBL560709 0.87 TSHR (0.73) TSHRCA12CA1CA2CA7
SCHEMBL27497678 0.87 ALDH1A1 (0.64) TSHRALDH1A1HSD17B10MAPK1TDP1
SCHEMBL4628574 0.85 TSHR (0.45) TSHRCA12CA1CA2CA7
SCHEMBL10562280 0.84 CA12 (0.59) TSHRCA12CA1CA2CA7
SCHEMBL11418791 0.84 TSHR (0.63) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117250294-A Method for detecting chlorophthalic acid in food by ethylation anti-interference 福建恒正检测技术有限公司 2023-12-19 CN disclosed
CN-102432712-B Catalyst component for ethylene polymerization and catalyst thereof CHINA PETROLEUM & CHEMICAL 2013-06-05 CN disclosed
CN-102432712-A Catalyst component for ethylene polymerization and catalyst thereof CHINA PETROLEUM & CHEMICAL 2012-05-02 CN disclosed
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 EP disclosed
EP-1209172-B1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2008-07-02 EP disclosed
CN-1215068-C Prepn process of 2,3,3',4'-diphenyl tetraformic dianhydride and its derivative CHANGCHUN APPLIED CHEMISTRY (CN) 2005-08-17 CN disclosed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
CN-1436780-A Prepn process of 2,3,3',4'-diphenyl tetraformic dianhydride and its derivative CHANGCHUN APPLIED CHEMISTRY (CN) 2003-08-20 CN disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX TSHR 4817/4885CA12 2609/4885CA1 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.