SCHEMBL4625619

SCHEMBL4625619

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)C1CC1)C(=O)COC(=O)C1CCCCC1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 10/20 0.78
▸ PGR P06401 5/20 0.78
▸ NR1I2 O75469 2/20 0.78
▸ MAPT P10636 2/20 0.78
▸ ADORA3 P0DMS8 2/20 0.78
▸ DRD2 P14416 1/20 0.78
▸ OPRD1 P41143 1/20 0.78
▸ CYP3A4 P08684 6/20 0.68
▸ MMP1 P03956 5/20 0.68
▸ USP2 O75604 5/20 0.68
▸ LMNA P02545 3/20 0.68
▸ SMN1; SMN2 Q16637 2/20 0.68
▸ CYP2C9 P11712 2/20 0.68
▸ MLNR O43193 1/20 0.68
▸ ABCB11 O95342 1/20 0.68
▸ CYP3A5 P20815 1/20 0.68
▸ PPARG P37231 1/20 0.68
▸ NPSR1 Q6W5P4 1/20 0.68
▸ CYP2D6 P10635 1/20 0.68
▸ MEN1 O00255 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4625625 1.00 NR3C1 (0.78) NR3C1PGRNR1I2MAPTADORA3
SCHEMBL4625624 1.00 NR3C1 (0.78) NR3C1PGRNR1I2MAPTADORA3
SCHEMBL9160605 0.97 NR3C1 (0.83) NR3C1PGRNR1I2MAPTADORA3
SCHEMBL11431304 0.91 NR3C1 (0.78) NR3C1PGRNR1I2MAPTADORA3
SCHEMBL11436665 0.90 NR3C1 (0.80) NR3C1PGRNR1I2MAPTADORA3
SCHEMBL11581106 0.90 NR3C1 (0.80) NR3C1PGRNR1I2MAPTADORA3
SCHEMBL11581104 0.90 NR3C1 (0.80) NR3C1PGRNR1I2MAPTADORA3
SCHEMBL4624240 0.89 NR3C1 (0.80) NR3C1PGRNR1I2MAPTCYP3A4
SCHEMBL4624245 0.89 NR3C1 (0.80) NR3C1PGRNR1I2MAPTCYP3A4
SCHEMBL4624243 0.89 NR3C1 (0.80) NR3C1PGRNR1I2MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295608-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OSTEOARTHRITIS INSIGNIA PHARMACEUTICALS, LLC (US) 2025-09-25 — — US claimed
US-20250288599-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OSTEOARTHRITIS INSIGNIA PHARMACEUTICALS, LLC (US) 2025-09-18 — — US claimed
CN-118853457-A Streptomyces, fermentation method for producing pteromycin glycoside and application thereof 中国科学院南海海洋研究所 2024-10-29 — — CN claimed
US-20230210868-A1 Methods of Treatment Using ICAM-Modulating Agents AVM BIOTECHNOLOGY, LLC (US) 2023-07-06 — — US claimed
US-8563731-B2 Mesylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]jamino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as agonist of the β2 adrenergic receptor ALMIRALL, S.A. (ES) 2013-10-22 — — US claimed
EP-1344526-B1 PREVENTIVES/REMEDIES FOR INFLAMMATORY AIRWAY DISEASES NIPPON SHINYAKU CO LTD (JP) 2008-05-28 — — EP claimed
US-7214672-B2 Preventives/remedies for inflammatory airway diseases NIPPON SHINYAKU CO., LTD. (JP) 2007-05-08 — — US claimed
US-20040053904-A1 Preventive/ermedies for inflammatory airway diseases NIPPON SHINYAKU CO., LTD. (JP) 2004-03-18 — — US claimed
CN-121950864-A Method for constructing milbemycin glycoside genetically engineered strain by utilizing glycosyltransferase and application 广州示康药业有限公司 2026-05-01 — — CN disclosed
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 — — EP disclosed
EP-4359402-B1 IMIDAZOLO INDAZOLE COMPOUNDS AS JAK INHIBITORS THERAVANCE BIOPHARMA R&D IP LLC (US) 2026-03-11 — — EP disclosed
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 — — US disclosed
US-20250276002-A1 Particles with RNA Cleaving Nucleobase Polymers and Uses for Managing Inflammatory Disorders UNIV EMORY (US) 2025-09-04 — — US disclosed
US-12398135-B2 Dimethyl amino azetidine amides as JAK inhibitors THERAVANCE BIOPHARMA R&D IP, LLC (US) 2025-08-26 — — US disclosed
US-20120329773-A1 BICYCLIC RING SYSTEM SUBSTITUTED AMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-12-27 — — US disclosed
US-20120316159-A1 BICYCLIC RING SYSTEM SUBSTITUTED SULFONAMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-12-13 — — US disclosed
US-7214672-B2 Preventives/remedies for inflammatory airway diseases NIPPON SHINYAKU CO., LTD. (JP) 2007-05-08 — — US disclosed
US-20050163724-A1 Powdery respiratory tonic composition SSP CO., LTD. (JP) 2005-07-28 — — US disclosed
EP-1514549-A1 POWDERY RESPIRATORY TONIC COMPOSITION SSP Co., Ltd. (JP) 2005-03-16 — — EP disclosed
US-20040053904-A1 Preventive/ermedies for inflammatory airway diseases NIPPON SHINYAKU CO., LTD. (JP) 2004-03-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053904-A1 Preventive/ermedies for inflammatory airway diseases NR3C1, OXER1, NR5A1 NR3C1 1/4885PGR 1911/4885NR1I2 249/4885
US-20120316159-A1 BICYCLIC RING SYSTEM SUBSTITUTED SULFONAMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS CXCR2, CCR2, SULT2A1 NR3C1 76/4885PGR 723/4885NR1I2 208/4885
US-12398135-B2 Dimethyl amino azetidine amides as JAK inhibitors JAK1, JAK2, JAK3 NR3C1 3546/4885PGR 3797/4885NR1I2 2756/4885
US-20120329773-A1 BICYCLIC RING SYSTEM SUBSTITUTED AMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS CXCR2, CCR2, CCR1 NR3C1 100/4885PGR 805/4885NR1I2 218/4885
US-20050163724-A1 Powdery respiratory tonic composition IL5, IL17A, RORC NR3C1 12/4885PGR 1432/4885NR1I2 614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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